| Specificity |
Proinsulin monoclonal antibodies (1A3D8, 1C6D6) recognize human proinsulin. |
| Host Species |
Mouse |
| Immunogen |
Human recombinant proinsulin |
| Species Reactivity |
Proinsulin monoclonal antibodies (1A3D8, 1C6D6) recognize human proinsulin. |
| Conjugate |
Unconjugated |
|
These antibodies are perfect choice for in vitro diagnostic assay development. And they are prepared for non‐clinical research use only. The recommended pairs are based on ourlaboratory results. |
| Application |
Recommended Usage |
| ELISA |
0.1-10 µg/ml |
|
| Form |
Liquid |
| Storage Buffer |
0.5mg/ml, in PBS buffer, pH 7.4, containing 0.02% sodium azide. |
| Concentration |
0.5 mg/ml |
| Storage Instructions |
Stored at ‐20°C or below until use. Avoid repeated freezing and thawing cycles. |
| Purification |
Protein A affinity column |
| Isotype |
Mouse IgG1,κ |
| Clonality |
Monoclonal |
| Clone ID |
1A3D8 |
| Target Background |
Proinsulin is the prohormone precursor to insulin made in the beta cells of the islets of Langerhans, specialized regions of the pancreas. It is synthesized in the endoplasmic reticulum, where it is folded and its disulfide bonds are oxidized. It is then transported to the Golgi apparatus where it is packaged into secretory vesicles, and where it is processed by a series of proteases to form mature insulin. Mature insulin has 35 fewer amino acids; 4 are removed altogether, and the remaining 31 forms C‐peptide. The C‐peptide is abstracted from the center of the proinsulin sequence; the two other ends (the B chain and A chain) remain connected by disulfide bonds.GenScript Human Proinsulin Antibody, mAb, Mouse is produced from the hybridomaresulting from fusion of SP2/‐Ag14 myeloma and B‐lymphocytes obtained from mouse immunized with human recombinant proinsulin. |
| Synonyms |
Proinsulin Antibody (1A3D8), mAb, Mouse; |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
