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Human C-peptide Antibody (4C2F10), mAb, Mouse

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C-peptide monoclonal antibodies (Clone 3E8D9, 8E10D3, 4C2F10 and 8G1D12) recognize human C-peptide and don’t cross-react with proinsulin and insulin.
A01784
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Specificity C-peptide monoclonal antibodies (Clone 3E8D9, 8E10D3, 4C2F10 and 8G1D12) recognize human C-peptide and don’t cross-react with proinsulin and insulin.
Host Species Mouse
Immunogen human C-peptide conjugated to KLH.
Conjugate Unconjugated

Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Sandwich ELISA Capture with A01784 and detected by A01726

Form Liquid
Storage Buffer 0.5 mg/ml, in PBS buffer, pH 7.4, containing 0.02% sodium azide.
Concentration 0.5 mg/ml
Storage Instructions For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Purification Protein A affinity column
Isotype Mouse IgG1,κ
Clonality Monoclonal
Clone ID 4C2F10

Target Background C-peptide serves as an important linker between A-chain and B-chain of insulin and facilitates the efficient assembly, folding, and processing of insulin in the endoplasmic reticulum. Equimolar amounts of C-peptide and insulin are stored in secretory granules of the pancreatic beta cells and both are eventually released to the portal circulation. The sole interest in C-peptide was as a marker of insulin secretion. Newly diagnosed diabetes patients often get their C-peptide levels measured as a means of distinguishing type 1 and type 2 diabetes. C-peptide is also used for determining the possibility of gastrinomas associated with Multiple Endocrine Neoplasm syndromes (MEN 1). GenScript Human C-Peptide Antibody, mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from mouse immunized with human C-peptide conjugated to KLH.
Synonyms Human C-peptide Antibody (4C2F10), mAb, Mouse;

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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