Human cMyBP-C Antibody (2G2F3)[Biotin], mAb, Mouse

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cMyBP-C is not essential for sarcomere formation during embryogenesis, but is crucial for sarcomere organization and maintenance of normal cardiac function. Absence of cMyBP-C results in severe cardiac hypertrophy, increased heart-weight-to-body-weight-ratios, enlargement of ventricles, increased myofilament Ca²⁺ sensitivity and depressed diastolic and systolic function. GenScript Anti-Human cMyBP-C Antibody (2G2F3)[Biotin], mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from a mouse immunized with recombinant human cMyBP-C expressed in mammalian cells.

产品编号	A01851
规格	定制报价

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产品概述

Specificity	The antibody specifically recognizes human cMyBP-C. The antibody is recommended as a detection antibody in vitro diagnostic assay development with capture antibody (GenScript, A01850-40, Anti-Human cMyBP-C Antibody (9B11C5), mAb, Mouse)
Host Species	Mouse
Immunogen	Recombinant human cMyBP-C

产品属性

Concentration	0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. (It could be customized for bulk order)
Reconstitution	Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
Purification	Protein A affinity column
Clone ID	2G2F3

技术背景

Target Background

cMyBP-C is not essential for sarcomere formation during embryogenesis, but is crucial for sarcomere organization and maintenance of normal cardiac function. Absence of cMyBP-C results in severe cardiac hypertrophy, increased heart-weight-to-body-weight-ratios, enlargement of ventricles, increased myofilament Ca²⁺ sensitivity and depressed diastolic and systolic function.
GenScript Anti-Human cMyBP-C Antibody (2G2F3)[Biotin], mAb, Mouse is produced from the hybridoma resulting from fusion of SP2/0-Ag14 myeloma and B-lymphocytes obtained from a mouse immunized with recombinant human cMyBP-C expressed in mammalian cells.