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CHO-K1/KIR Stable Cell Line


Synonyms NKAT; NKAT1; p58.1; CD158A; KIR221; NKAT-1; KIR-K64
Description Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and are subsets of T cells. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Species Human
Culture Medium F12K, 10% FBS, 8 μg/ml Puromycin
Freeze Medium 95% complete growth medium, 5% DMSO

Stability 15 passages
Storage Liquid nitrogen immediately upon receiving

CHO-K1/KIR Stable Cell Line
CHO-K1/KIR Stable Cell Line

FACS analysis of KIR expression in CHO-K1 cells.




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产品编号: M00650
规格
价格
数量
2 vials ¥85000