GPCR和离子通道稳定细胞系

金斯瑞为客户提供种类丰富的GPCR和离子通道稳定细胞系。凭借密码子优化和载体设计的专利技术,我们成功克服了细胞表面功能蛋白表达水平低的难题。金斯瑞所有的细胞系均针对钙流检测或其他检测中的信背比(S/B ratio)进行了优化,并通过了16次传代的稳定性验证。另外,金斯瑞还提供稳定细胞系的构建服务,以满足您的特殊需求。

服务特色

  • 细胞表面功能蛋白表达水平高
  • 实验结果可靠,可重现
  • 所有的离子通道稳定细胞系都通过手动膜片钳和Qpatch验证
  • 多种功能参数可供选择

GPCR稳定细胞系

超家族
配体类型
受体家族
受体
细胞系名称
产品编号
A
Non-peptide Acetylcholine (muscarinic) M1 / CHRM1 CHO-K1/M1
M00185
A
Non-peptide Acetylcholine (muscarinic) M2 / CHRM2 CHO-K1/M2/Gα15
M00258
A
Non-peptide Acetylcholine (muscarinic) M3 / CHRM3 CHO-K1/M3
M00259
A
Non-peptide Acetylcholine (muscarinic) M4 / CHRM4 CHO-K1/M4/Gα15
M00238
A
Non-peptide Acetylcholine (muscarinic) M5 / CHRM5 CHO-K1/M5
M00186
A
Non-peptide Adenosine ADORA1 CHO-K1/ADORA1/Gα15
M00324
A
Non-peptide Adenosine ADORA1 293/ADORA1/Gα15
M00255
A
Non-peptide Adenosine ADORA2A CHO-K1/ADORA2A/Gα15
M00246
A
Non-peptide Adenosine ADORA2B CHO-K1/ADORA2B/Gα15
M00329
A
Non-peptide Adenosine ADORA3 CHO-K1/ADORA3/Gqi5
M00464
A
Non-peptide Adrenoceptors ADRA1A CHO-K1/ADRA1A
M00225
A
Non-peptide Adrenoceptors ADRA1B CHO-K1/ADRA1B
M00260
A
Non-peptide Adrenoceptors ADRA1D CHO-K1/ADRA1D
M00340
A
Non-peptide Adrenoceptors ADRA2A CHO-K1/ADRA2A/Gα15
M00281
A
Non-peptide Adrenoceptors ADRA2B CHO-K1/ADRA2B/Gqi5
M00454
A
Non-peptide Adrenoceptors ADRA2C CHO-K1/ADRA2C/Gα15
M00252
A
Non-peptide Adrenoceptors ADRB1 CHO-K1/ADRB1/Gα15
M00269
A
Non-peptide Adrenoceptors ADRB2 CHO-K1/ADRB2/Gα15
M00308
A
Non-peptide Adrenoceptors ADRB3 293/ADRB3/CRE-Luc
M00335
A
Peptide Anaphylotoxin C5a / C5AR1 CHO-K1/C5a/Gα15
M00327
A
Peptide Angiotensin AT1 293T/AT1
M00448
A
Peptide Angiotensin AT1 HEK293/AT1
M00458
A
Peptide Apelin AGTRL1 CHO-K1/AGTRL1/Gα15
M00245
A
Non-peptide Bile acid GPBAR1 CHO-K1/GPBAR1
M00432
A
Peptide Bombesin BB1 / NMBR CHO-K1/BB1
M00254
A
Peptide Bombesin BB2 / GRPR CHO-K1/BB2
M00182
A
Peptide Bombesin BB3 / BRS3 CHO-K1/BB3
M00183
A
Peptide Bradykinin B1 / BDKRB1 CHO-K1/B1/Gα15
M00482
A
Peptide Bradykinin B2 / BDKRB2 CHO-K1/B2/Gα15
M00184
A
Non-peptide Cannabinoid CB1 / CNR1 CHO-K1/CB1/Gα15
M00299
A
Non-peptide Cannabinoid CB2 / CNR2 CHO-K1/CB2
M00433
A
Peptide Chemoattractant ChemR23 / CMKLR1 CHO-K1/CMKLR1/Gα15
M00301
A
Peptide Cholecystokinin CCKA CHO-K1/CCKA/Gα15
M00271
A
Peptide Cholecystokinin CCKB CHO-K1/CCKB
M00154
A
Non-peptide Dopamine D1 / DRD1 CHO-K1/D1
M00247
A
Non-peptide Dopamine D2 / DRD2 CHO-K1/D2/Gα15
M00152
A
Non-peptide Dopamine D2S / DRD2S CHO-K1/D2S/Gα15
M00274
A
Non-peptide Dopamine D4 / DRD4 293/D4
M00477
A
Non-peptide Dopamine D5 / DRD5 CHO-K1/D5/Gα15
M00322
A
Peptide Endothelin EDNRA CHO-K1/EDNRA
M00149
A
Peptide Endothelin EDNRB CHO-K1/EDNRB
M00150
A
Non-peptide Free Fatty Acid FFA1 / GPR40 CHO-K1/FFA1/Gα15
M00273
A
Non-peptide Free Fatty Acid FFA2 / GPR43 CHO-K1/FFA2/Gα15
M00437
A
Peptide Galanin GAL1 CHO-K1/GAL1/Gα15
M00277
A
Peptide Galanin GAL2 CHO-K1/GAL2
M00209
A
Peptide Ghrelin GHSR CHO-K1/GHSR
M00189
A
Peptide Gonadotropin-releasing Hormone GNRHR CHO-K1/GNRHR/Gα15
M00426
A
Non-peptide Histamine H1 293/H1
M00131
A
Non-peptide Histamine H2 CHO-K1/H2/Gα15
M00306
A
Non-peptide Histamine H3 CHO-K1/H3/Gα15
M00331
A
Non-peptide Histamine H4 CHO-K1/H4/Gα15
M00289
A
Peptide KiSS1-derived Peptide KiSS1 / GPR54 CHO-K1/KiSS1
M00190
A
Non-peptide Leukotriene CysLT1 CHO-K1/CysLT1/Gα15
M00462
A
Non-peptide Leukotriene CysLT2 CHO-K1/CysLT2
M00449
A
Non-peptide Leukotriene LTB4 CHO-K1/LTB4/Gα15
M00435
A
Non-peptide Leukotriene OXE / OXER1 CHO-K1/OXE-Flag/Gα15
M00488
A
Non-peptide Lysophospholipid EDG4 / LPA2 RH7777/EDG4
M00463
A
Non-peptide Lysophospholipid EDG6 / S1P4 RH7777/EDG6
M00465
A
Peptide Melanin-concentrating Hormone MCH1 293/MCH1
M00211
A
Peptide Melanin-concentrating Hormone MCH2 CHO-K1/MCH2
M00280
A
Peptide Melanocortin MC2 CHO-K1/MC2/Gα15
M00336
A
Peptide Melanocortin MC3 CHO-K1/MC3/Gα15
M00242
A
Peptide Melanocortin MC3 293/MC3/CRE-Luc
M00337
A
Peptide Melanocortin MC4 CHO-K1/MC4/Gα15
M00272
A
Peptide Melanocortin MC5 CHO-K1/MC5/Gα15
M00243
A
Peptide Melatonin MT1 / MTNR1A CHO-K1/MT1/Gα15
M00424
A
Peptide Melatonin MT2 / MTNR1B CHO-K1/MT2/Gα15
M00312
A
Peptide Motilin MTLR CHO-K1/MTLR/Gα15
M00347
A
Peptide Neuromedin U NMU1 CHO-K1/NMU1
M00191
A
Peptide Neuromedin U NMU2 293T/NMU2
M00244
A
Peptide Neuropeptide B/W NPBW1 / GPR7 CHO-K1/NPBW1/Gα15
M00452
A
Peptide Neuropeptide FF NPFF1 / GPR147 CHO-K1/NPFF1/Gα15
M00431
A
Peptide Neuropeptide FF NPFF2 / GPR74 CHO-K1/NPFF2/Gα15
M00474
A
Peptide Neuropeptide S NPS1a CHO-K1/NPS1a/Gα15
M00338
A
Peptide Neuropeptide S NPS1b CHO-K1/NPS1b/Gα15
M00344
A
Peptide Neuropeptide Y NPY1 CHO-K1/NPY1/Gα15
M00192
A
Peptide Neuropeptide Y NPY1 293/NPY1
M00430
A
Peptide Neuropeptide Y NPY2 CHO-K1/NPY2/Gqi5
M00460
A
Peptide Neuropeptide Y NPY4 / PPYR1 CHO-K1/NPY4/Gα15
M00237
A
Peptide Neurotensin NTS1 CHO-K1/NTS1
M00194
A
Non-peptide Nicotinic Acid NIACR1 / GPR109A CHO-K1/NIACR1/Gα15
M00428
A
Peptide N-Formyl Peptide FPR1 CHO-K1/FPR1/Gα15
M00429
A
Peptide N-Formyl Peptide FPRL1 CHO-K1/FPRL1/Gα15
M00305
A
Peptide Opioid OPRD1 CHO-K1/OPRD1/Gα15
M00323
A
Peptide Opioid OPRK1 CHO-K1/OPRK1/Gα15
M00290
A
Peptide Opioid OPRL1 CHO-K1/OPRL1/Gα15
M00447
A
Peptide Opioid OPRM1 CHO-K1/OPRM1/Gα15
M00304
A
Peptide Orexin OX1 CHO-K1/OX1
M00224
A
Peptide Orexin OX2 CHO-K1/OX2
M00316
A
Peptide Oxytocin OT / OXTR CHO-K1/OXTR
M00195
A
Peptide Peptide P518 GPR103 CHO-K1/GPR103/Gα15
M00321
A
Non-peptide Platelet Activating Factor PAF / PTAFR CHO-K1/PTAFR
M00262
A
Peptide Prolactin Releasing Peptide PRLHR CHO-K1/PRLHR
M00341
A
Non-peptide Prostanoid DP1 / PTGDR CHO-K1/DP1/Gα15
M00453
A
Non-peptide Prostanoid DP2 / GPR44 CHO-K1/DP2/Gα15
M00436
A
Non-peptide Prostanoid FP / PTGFR 293/FP/Gα15
M00155
A
Non-peptide Prostanoid EP1 / PTGER1 293/EP1
M00228
A
Non-peptide Prostanoid EP2 / PTGER2 CHO-K1/EP2/Gα15
M00311
A
Non-peptide Prostanoid EP4 / PTGER4 293/EP4
M00485
A
Non-peptide Prostanoid IP1 / PTGIR CHO-K1/IP1/Gα15
M00310
A
Non-peptide Prostanoid TP / TBXA2R 293/TP
M00309
A
Peptide Proteinase-activated Receptor PAR2 / F2RL1 CHO-K1/PAR2/Gα15
M00446
A
Peptide Proteinase-activated Receptor PAR4 / F2RL3 CHO-K1/PAR4
M00206
A
Non-peptide Proton-sensor GPR68 CHO-K1/GPR68/Gα15
M00439
A
Non-peptide Purinergic P2Y1 1321N1/P2Y1
M00250
A
Non-peptide Purinergic P2Y2 1321N1/P2Y2
M00318
A
Non-peptide Purinergic P2Y4 1321N1/P2Y4
M00297
A
Non-peptide Purinergic P2Y6 1321N1/P2Y6
M00346
A
Non-peptide Purinergic P2Y11 1321N1/P2Y11
M00298
A
Non-peptide Purinergic P2Y12 1321N1/P2Y12/Gα15
M00261
A
Non-peptide Serotonin 5-HT1A / HTR1A CHO-K1/5-HT1A/Gα15
M00330
A
Non-peptide Serotonin 5-HT2A / HTR2A CHO-K1/5-HT2A
M00251
A
Non-peptide Serotonin 5-HT2B / HTR2B CHO-K1/5-HT2B
M00249
A
Non-peptide Serotonin 5-HT2C / HTR2C CHO-K1/5-HT2C
M00253
A
Non-peptide Serotonin 5-HT2C / HTR2C HEK293/5-HT2C
M00319
A
Non-peptide Serotonin 5-HT4 / HTR4 CHO-K1/5-HT4/Gα15
M00444
A
Non-peptide Serotonin 5-HT7 / HTR7 293/5-HT7/CRE-Luc
M00423
A
Peptide Somatostatin SST1 CHO-K1/SST1/Gqi5
M00473
A
Peptide Somatostatin SST2 CHO-K1/SST2/Gα15
M00325
A
Peptide Somatostatin SST3 CHO-K1/SST3/Gα15
M00285
A
Peptide Somatostatin SST4 CHO-K1/SST4/Gα15
M00334
A
Peptide Somatostatin SST5 CHO-K1/SST5/Gα15
M00286
A
Peptide Tachykinin NK1 / TACR1 CHO-K1/NK1
M00199
A
Peptide Tachykinin NK2 / TACR2 CHO-K1/NK2
M00200
A
Peptide Tachykinin NK3 / TACR3 CHO-K1/NK3
M00201
A
Peptide Thyrtropin-releasing Hormone TRH1 CHO-K1/TRH1
M00202
A
Peptide Urotensin UT2 CHO-K1/UT2/Gα15
M00339
A
Peptide Vasopressin V1A / AVPR1A CHO-K1/V1A
M00181
A
Peptide Vasopressin V1B / AVPR1B CHO-K1/V1B
M00205
A
Peptide Vasopressin V2 / AVPR2 CHO-K1/V2/Gα15
M00170
A
  Orphan GPR120 CHO-K1/GPR120/Gα15
M00440
A
  Orphan MRGD / MRGPRD CHO-K1/MRGPRD/Gα15
M00467
A
  Orphan MRGX2 / MRGPRX2 CHO-K1/MRGPRX2
M00425
A
  Orphan OXGR1 CHO-K1/OXGR1/Gα15
M00483
A
  Orphan P2Y5 RH7777/P2Y5
M00472
A
  Orphan SUCNR1 / GPR91 CHO-K1/SUCNR1/Gα15
M00471
B
Peptide Calcitonin CALCR / CT CHO-K1/CT/Gα15
M00320
B
Peptide Calcitonin AMY1 (RAMP1 + CALCR) CHO-K1/AMY1/CRE-Luc
M00350
B
Peptide Calcitonin AMY1 (RAMP1 + CALCR) CHO-K1/AMY1/Gα15
M00475
B
Peptide Calcitonin AMY2 (RAMP2 + CALCR) CHO-K1/AMY2/Gα15
M00478
B
Peptide Calcitonin AMY3 (RAMP3 + CALCR) CHO-K1/AMY3/Gα15
M00481
B
Peptide Calcitonin AM1 (RAMP2 + CALCRL) CHO-K1/AM1
M00450
B
Peptide Calcitonin AM2 (RAMP3 + CALCRL) CHO-K1/AM2/Gα15
M00479
B
Peptide Corticotropin Releasing Factor CRF1 CHO-K1/CRF1/Gα15
M00343
B
Peptide Corticotropin Releasing Factor CRF2 CHO-K1/CRF2/Gα15
M00208
B
Peptide Glucagon GCGR CHO-K1/GCGR/Gα15
M00345
B
Peptide Glucagon GCGR HEK293/GCGR/Gα15
M00422
B
Peptide Glucagon GHRH 293/GHRH/Gα15
M00314
B
Peptide Glucagon GIP CHO-K1/GIP/Gα15
M00486
B
Peptide Glucagon GLP1 CHO-K1/GLP1/Gα15
M00451
B
Peptide Glucagon GLP2 CHO-K1/GLP2/Gα15
M00307
B
Peptide Glucagon SCTR CHO-K1/SCTR/Gα15
M00326
B
Peptide Parathyroid Hormone PTH1 CHO-K1/PTH1/Gα15
M00315
B
Peptide Parathyroid Hormone PTH2 293/PTH2/CRE-Luc
M00270
B
Peptide VIP / PACAP PAC1 CHO-K1/PAC1/Gα15
M00203
B
Peptide VIP / PACAP VPAC1 CHO-K1/VPAC1/Gα15
M00342
B
Peptide VIP / PACAP VPAC2 CHO-K1/VPAC2/Gα15
M00226
C
Non-peptide Calcium-sensor CASR CHO-K1/CASR
M00434
C
Non-peptide Glutamate mGlu2 / GRM2 CHO-K1/GRM2/Gα15
M00427
    Control   CHO-K1/CRE-Luc
M00187
    Control   293/CRE-Luc
M00188
    Control   CHO-K1/Gα15
M00257
    Control   CHO-K1/Gqi5
M00455

用于筛选模型开发的稳定细胞系服务

服务编号 服务名称
价格(¥)
SC1394
用于筛选模型开发的稳定细胞系服务
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