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Covalent inhibition of NSD1 histone methyltransferase

Authors: Huang H, Howard CA, Zari S, Cho HJ, Shukla S, Li H, Ndoj J, González-Alonso P, Nikolaidis C, Abbott J, Rogawski DS, Potopnyk MA, Kempinska K, Miao H, Purohit T, Henderson A, Mapp A, Sulis ML, Ferrando A, Grembecka J, Cierpicki T

Journal: Nature Chemical Biology

PubMed ID: 32868895

Doi: 10.1038/s41589-020-0626-6

Products & Services: Proteins, Expression, Isolation and Analysis

A vector whitefly endocytic receptor facilitates the entry of begomoviruses into its midgut cells via binding to virion capsid proteins

Authors: Jing Zhao, Teng Lei, Xin-Jia Zhang, Tian-Yan Yin, Xiao-Wei Wang, Shu-Sheng Liu

Journal: PLoS Pathog

PubMed ID: 33270808

Doi: 10.1371/journal.ppat.1009053

Products & Services: Proteins, Expression, Isolation and Analysis Molecular Biology Reagents

Targeting Thymidine Phosphorylase With Tipiracil Hydrochloride Attenuates Thrombosis Without Increasing Risk of Bleeding in Mice

Authors: Adam Belcher, Abu Hasanat Md Zulfiker, Oliver Qiyue Li, Hong Yue, Anirban Sen Gupta, Wei Li

Journal: Arterioscler Thromb Vasc Biol

PubMed ID: 33297751

Doi: 10.1161/ATVBAHA.120.315109

Products & Services: Proteins, Expression, Isolation and Analysis

Nrl Is Dispensable for Specification of Rod Photoreceptors in Adult Zebrafish Despite Its Deeply Conserved Requirement Earlier in Ontogeny

Authors: Oel AP,Neil GJ,Dong EM,Balay SD,Collett K,Allison WT

Journal: iScience

PubMed ID: 33299975

Doi: 10.1016/j.isci.2020.101805

Products & Services: Proteins, Expression, Isolation and Analysis

Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation

Authors: Deol KK, Crowe SO, Du J, Bisbee HA, Guenette RG, Strieter ER

Journal: Molecular Cell

PubMed ID: 33156996

Doi: 10.1016/j.molcel.2020.10.017

Products & Services: Proteins, Expression, Isolation and Analysis

Production of indigo through the use of a dual-function substrate and a bifunctional fusion enzyme

Authors: Fabara AN,Fraaije MW

Journal: Enzyme and Microbial Technology

PubMed ID: 33220871

Doi: 10.1016/j.enzmictec.2020.109692

Products & Services: Proteins, Expression, Isolation and Analysis

Specific determination of hepatitis B e antigen by antibodies targeting precore unique epitope facilitates clinical diagnosis and drug evaluation against hepatitis B virus infection

Authors: Shao-Juan Wang, Zi-Min Chen, Min Wei, Jia-Qi Liu, Zong-Lin Li, Tian-Shu Shi, Sheng Nian, Rao Fu, Yang-Tao Wu, Ya-Li Zhang, Ying-Bin Wang, Tian-Ying Zhang, Jun Zhang, Jun-Hui Xiong, Shu-Ping Tong, Sheng-Xiang Ge, Quan Yuan, Ning-Shao Xia

Journal: Emerg Microbes Infect

PubMed ID: 33296295

Doi: 10.1080/22221751.2020.1862631

Products & Services: Proteins, Expression, Isolation and Analysis

One-Pot Synthesis of a Bis-Thio-Acetone Linked Ubiquitinated Histones Using 1,3-Dibromoacetone

Authors: Guo-Chao Chu, Rui Zhao, Xiangwei Wu, Jing Shi, Yi-Ming Li

Journal: J Org Chem.

PubMed ID: 33191736

Doi: 10.1021/acs.joc.0c01851.

Products & Services: Proteins, Expression, Isolation and Analysis

Chronic copper exposure directs microglia towards degenerative expression signatures in wild-type and J20 mouse model of Alzheimer's disease

Authors: Lim SL, Rodriguez-Ortiz CJ, Hsu HW, Wu J, Zumkehr J, Kilian J, Vidal J, Ayata P, Kitazawa M