The 2nd Synthetic Biology World Forum 2019 (Nanjing) Agenda
会场: 2楼 百家湖
13:00-13:40
The 2nd Synthetic Biology World Forum (SBWF) 2019 Opening Ceremony and Greetings
Host: Dr. Zhu Li, VP of Corporate Development, GenScript
13:40-14:10
Plenary Speech
Host: Prof. Min Jiang, Nanjing Tech University
14:10-14:40
Guoping Zhao, Institute of Plant Physiology and Ecology, Shanghai Institute of Biological Sciences
14:40-15:10
Jay D. Keasling, University of California, Berkeley
15:10-15:40
Akihiko Kondo, Kobe University
Development of microbial cell factories for consolidated bioprocessing by engineering biology platform
15:40-16:00
Coffee Break
16:00-16:30
Qipeng Yuan, Beijing University Of Chemical Technology
Strategies for construction of efficient microbial cell factories: enzyme, pathway and metabolic network
16:30-17:00
Sang Jun Sim, Korea University
Conversion of waste CO2 into green gold microalgae From micro- to macro-scale approaches
17:00-17:30
Penjit Srinophakun, President of the Thai Society for Biotechnology
Synthesized Platform of Biodiesel and Biochemicals
17:30-18:00
Ping Xu, Shanghai Jiao Tong University
Molecular microbiology: Enzymes and value-added chemicals via microbial catabolism of environmental molecules
18:00-20:00
Welcome Dinner by Invitation
Session 1
Session 2
Session 3
Session 4
Session 5
Session 1 Dawn of smart biomanufacturing: innovative tools and applications in synthetic biology
Chair:
Jianjun Qiao, Tianjin University
Jeff Tabor, Rice University
会场: 2楼 百家湖 B
8:30-8:55
Jianjun Qiao, Tianjin University
Construction of Lactococcus lactis chassis cells with high nisin yield
8:55-9:20
Long Liu, Jiangnan University
Synthetic genetic circuits for dynamic fine-tuning of metabolic modules in Bacillus subtilis
9:20-9:40
I-Son Ng, National Cheng Kung University
Genome editing by CRISPR system in microalgae
9:40-10:00
Yu Zhang, Science of Plant Physiology and Ecology, CAS
Structural basis for bacterial transcription activation
10:00-10:20
Coffee Break
10:20-10:45
Jeff Tabor, Rice University
Bacterial two-component systems: a treasure trove of sensors for synthetic biology applications
10:45-11:10
Cedric Wu, GenScript
Rapid assembly of gene variant libraries and multi-gene pathways with semiconductor technologies
11:10-11:30
Zhoutong Sun, Tianjin Institute of Industrial Biotechnology, CAS
The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes
11:30-11:50
Kaiyue Wu, Beckman
The revolution in synthetic biology
11:50-12:10
Lujia Zhang, East China Normal University
Regulation of primary and secondary reactions of nitrilase (3)
Session 2 Natural product transformation and metabolic engineering
Chair:
Tiangang Liu, Wuhan University
Christina Smolke, Stanford University
会场: 2楼 东山
8:30-8:55
Tiangang Liu, Wuhan University
Production of Carotenoids by Chassis Engineering and Modular Enzyme Assembly in Microbe
8:55-9:20
Shouwen Chen, Hubei University
Construction of the metabolic engineering platform of Bacillus licheniformis
9:20-9:40
Yu Wang, Tianjin Institute of Industrial Biotechnology, CAS
Genome engineering of Corynebacterium glutamicum as a chassis for bioconversion of C1 feedstocks
9:40-10:00
Jifeng Yuan, Xiamen University
Synthesis and accumulation of aromatic aldehyde derived compounds in yeast
10:00-10:20
Coffee Break
10:20-10:45
Kui Hong, Wuhan University
Sesterterpene biosynthesis: from marine fungus Aspergillus sp. to E. coli
10:45-11:10
YaPing Xue, Zhejiang University of Technology
Efficient synthetic system for production of microbial drugs
11:10-11:30
Dawei Zhang, Tianjin Institute of Industrial Biotechnology
De novo biosynthesis of vitamin B12 in E. coli
11:30-11:50
Yan Qiao, Institute of Chemistry Chinese Academy of Sciences
Synthetic cellularity and community in chemical system
11:50-12:10
Lidan Ye, Zhejiang University
Engineering Saccharomyces cerevisiae for biosynthesis of antioxidants
Session 3 Synthetic biology for Biochemicals and Biomaterials
Chair:
Guocheng Du, Jiangnan University
Penjit Srinophakun, Thai Society for Biotechnology
会场: 2楼 湖熟
8:30-8:55
Jianmin Xing, Institute of process engineering, CAS
Enhanced growth-driven stepwise inducible expression system development in haloalkaliphilic desulfurizing bacteria Thioalkalivibrio versutus
8:55-9:15
Xiaoxia Xia, Shanghai Jiao Tong University
A Synthetic Biology Approach for Making Spider Silk: From Gene Design to Fabrication
9:15-9:35
Yao Chen, Nankai University
Biomolecule-incorporation: Novel composite materials for biocatalytic and medical applications
9:35-9:55
Daochen Zhu, Jiangsu University
Bioconversion of lignin into high value aromatic compounds by bacteria
9:55-10:15
Coffee Break
10:15-10:40
Hongwu Ma, Tianjin Institute of Industrial Biotechnology, CAS
Computational Design of Novel one-carbon assimilation pathways
10:40-11:05
Taek Soon Lee, Lawrence Berkeley National Lab
Synthetic biology to engineer E. coli as more industrially applicable host
11:05-11:25
Chun You, Tianjin Institute of Industrial Biotechnology, CAS
The construction of in vitro synthetic enzymatic biosystem and its industrial application
11:25-11:45
YanFeng Liu, Jiangnan University
Synthetic N-terminal coding sequences for fine-tuning gene expression and metabolic engineering in Bacillus subtilis
11:45-12:05
Quanshun Li, Jilin University
Biocatalytic synthesis of polymeric materials for biomedical applications
12:05-12:25
Aitao Li, Hubei University
P450 Monooxygenases Mediated Artificial Biosynthetic Pathways Construction for Chemical Synthesis
Session 4 Genetically reprogrammed microbes as living therapeutics or cell factories of pharmaceuticals
Chair:
Dr. Li, VP of Corporate Devlopment, GenScript
John Dueber, University of California, Berkeley
会场: 2楼 汤山
8:30-8:55
Zhen Xie, Tsinghua University
Smart Drugs Research based on Synthetic Genetic Circuits
8:55-9:20
Shawn Zhou, GenScript
Accelerate Next-generation Cell Therapy development with CRISPR technology
9:20-9:40
Zhen Liu, Beijing University Of Chemical Technology
Bio-formulation Engineering-Guided Design and Synthesis of Biomaterials towards Clinical Applications
9:40-10:00
Guangyu Yang, Shanghai Jiao Tong University
Directed evolution of glycosyltransferase for the artificial biosynthesis of natural product glycosides
10:00-10:20
Yanfen Cheng, Nanjing Agricultural University
Role of gastrointestinal microbes in the metabolism of nutrients and animal health
10:20-10:40
Coffee Break
10:40-11:05
Jingwen Zhou, Jiangnan University
Towards the industrial scale production of important flavonoids with microorganisms
11:05-11:30
John Dueber, University of California
Repurposing the peroxisome to compartmentalize engineered metabolism
11:30-11:50
Han Xiao, Shanghai Jiao Tong University
Towards efficient bioproduction of anti-tumor ganoderic acids (GAs): genome editing and synthetic biology approaches
11:50-12:10
Dan Wang, Chongqing University
A nature inspired route toward the synthesis of nonnatural straight-chain amino acids
Session 5 Bioenergy and the 3rd international Symposium on Zymomonas mobilis
Chair:
Bruce Dale, Michigan State University
Mingjie Jin, Nanjing University of Science and Technology
会场: 2楼 百家湖 A
8:30-8:55
Bruce Dale, Michigan State University
Rethinking Cellulosic Ethanol (and Other Cellulosic Biofuels)
8:55-9:20
Shangtian Yang, Ohio State University
Engineering clostridia for n-butanol production from lignocellulosic biomass
9:20-9:45
Yingxiu Cao, Tianjin University
High production of fatty alcohols in Yarrowia lipolytica by coordination with glycolysis
9:45-10:05
Tatsaporn Todhanakasem, Assumption University
Zymomonas mobilis biofilm reactor using lignocellulosic materials as substrates
10:05-10:25
Chenguang Liu, Shanghai Jiao Tong University
Redox potential regulation improves yeast cells productivity and stress tolerance
10:25-10:45
Coffee Break
10:45-11:10
Jie Bao, East China University of Science and Technology
Global transcriptome and metabolic engineering of Zymomonas mobilis toward the inhibitor tolerant cells
11:10-11:35
Robert Landick, University of Wisconsin-Madison
Biodesign of Zymomonas mobilis as a chassis for lignocellulosic bioproduct synthesis
11:35-12:00
Mamoru Yamada, Yamaguchi University
Genomic aspects of thermotolerance of mesophilic microorganisms
12:00-12:20
Yirui Wu, Shantou University
Metabolic analysis of biobutanol production by a newly Clostridium sp. strain WK with high butyrate-tolerant and pH-independent properties
Session 1
Session 2
Session 5
Session 6
Session 1 Dawn of smart biomanufacturing: innovative tools and applications in synthetic biology
Chair:
Peter Zhao, R&D Director, MappleBio
Vel Murugan, Arizona State University
会场: 2楼 百家湖 B
14:00-14:25
Vel Murugan, Arizona State University
Synthetic Biology in Rapid Biomarker Discovery and Development
14:25-14:50
Harry Zhang, Fudan University
Droplet Microfluidics for High Throughput Biochemical Assays
14:50-15:10
Lihua Zhang, MolecularCloud
Easier Way Working with DNA for the Future Science
15:10-15:30
Xinqing Zhao, Shanghai Jiao Tong University
Enhancing production of cellulosic enzymes by the filamentous fungus Trichoderma reesei using artificial transcription factors
15:30-15:50
Coffee Break
15:50-16:15
Chong Zhang, Tsinghua University
Data-driven tailoring design of biological systems: from data collection to algorithms development
16:15-16:35
Nicholas C. Butzin, South Dakota State University
Using synthetic biology to explore bacterial tolerance, persistence, and antibiotic resistance
16:35-16:55
Yu Deng, Jiangnan University
DeepEDR, a deep-learning based method to enhance biosensor dynamic range
Panel Discussion
16:55-17:45
Vel Murugan, Harry Zhang, Hongwu Ma, Chong Zhang
Computer and Artificial Intelligence in Gene Design Applications
Session 2 Natural product transformation and metabolic engineering
Chair:
Ping Xu, Shanghai Jiaotong University
Robert Landick, University of Wisconsin–Madison
会场: 2楼 东山
14:00-14:25
Christina Smolke, Stanford University
Biosynthesis of complex plant-derived natural products
14:25-14:50
Congqiang Zhang, Agency for science, technology and research (A*STAR), Singapore
Microbial discovery and production of terpene synthases and isoprenoids
14:50-15:10
Yixin Huo, Beijing Institute of Technology
Screening overproduction strains for value-added chemicals based on transcriptional and translational regulations
15:10-15:30
Shangxian Xie, Huazhong University of Science and Technology
Lignin Biodegradation and Valorization with Synthetic Bacteria
15:30-15:50
Coffee Break
15:50-16:15
Lianghui Ji, National University of Singapore
Exploiting the carotenoid and triacylglycerol biosynthesis pathways of red yeast for industrial production of high-valued fatty acids and terpenoids
16:15-16:40
Hao Song, Tianjin University
Engineering intracellular and extracellular electron pathways for cellular energy metabolism
16:40-17:05
Jiaoqi Gao, Dalian Institute of Chemical Physics, CAS
Precise CRISPR-Cas9 based genome editing in methylotrophic yeast Ogataea polymorpha
17:05-17:25
Shuobo Shi, Beijing University Of Chemical Technology
Microbial-based production of fatty acid-derived products
17:25-17:45
Jianmei Luo, Tianjin University of Science & Technology
The global regulator enhances organic solvent tolerance and Δ1‑dehydrogenation productivity of Arthrobacter simplex
Session 5 Bioenergy and the 3rd international Symposium on Zymomonas mobilis
Chair:
Jie Bao, East China University of Science and Technology
Ed Bayer, The Weizmann Institute of Science
会场: 2楼 百家湖 A
14:00-14:25
Zongbao Zhao, Dalian Institute of Chemical Physics, CAS
Engineering the red yeast R. toruloides
14:25-14:50
Jian Xu, Qingdao Institute of Bioenergy and Bioprocess Technology, CAS
When synthetic biology meets single-cell technology: developing Nannochloropsis into microalgal cell factory of "designer oils" from CO2 and seawater
14:50-15:15
Mingxiong He, Biogas Institute of Ministry of Agriculture
Replacing Water and Nutrients for Ethanol Production by Zymomonas mobilis Strain
15:15-15:35
Jufang Wang, South China University of Technology
Metabolic engineering of Clostridium tyrobutyricum for enhanced butyric acid production from renewable biomass
15:35-15:55
Coffee Break
15:55-16:20
James McKinlay, Indiana University
The benefits of N2 and the toxicity of O2 for ethanol-producing Zymomonas mobilis
16:20-16:45
Ed Bayer The Weizmann Institute of Science
Designer cellulosomes as a broad platform for synthetic biotechnology
16:45-17:05
Yuanyuan Ma, Tianjin University
Butanol-tolerant mechanism of Escherichia coli mutants and construction of high-resistant strains
17:05-17:25
Zhiqiang Wen, Nanjing University of Science and Technology
Design and regulation of synthetic microbial communities to produce butanol by consolidated processing
17:25-17:45
Chuang Xue, Dalian University of Technology
Cell and process engineering of Clostridium acetobutylicum for biobutanol production
Session 6 Industry prospects, technological transformation and investment exchange of synthetic biology
Chair:
Dr. Kening Li, VP of Corporate Development, GenScript
会场: 2楼 汤山
14:00-14:25
吴朝晖, 中国生物医药技术协会秘书长
我国细胞治疗的政策趋势
14:25-14:50
Dungang Mou
High Throughput Mini Bioreactor Design for Culture Robustness and Predictive Scale Up
Panel Discussion 1
14:50-15:40
Guests: Dr. Zhu Li, VP of GenScript; Forest Zhong, Investor; 吴应光, 贝克曼中国区GM; 欧阳晖, 远大医药CSO
中国基因治疗技术发展前瞻，市场需求预测和政策导向建议
15:40-16:00
Coffee Break
16:00-16:30
Michael Chen, VP of External Innovation Merck KGaA
Merck 外部创新的回顾和产业合作计划
Panel Discussion 2
16:30-17:20
Guests: 谢震, 合成生物技术协会会长； 徐健，青岛生物能源与过程研究所；李勉，浙江华康药业首席科学家； Robert Landick, University of Wiscon, Madison
新能源开发和应用的技术突破，国内外应用领域对比以及未来机会展望
Session 2
Session 5
Session 7
Session 2 Natural product transformation and metabolic engineering
Chair:
Zongbao Zhao, Dalian Institute of Chemical Physics, CAS
Qingsheng Qi, Shan Dong University
会场: 2楼 东山
8:30-8:55
Qingsheng Qi, Shandong University
Sensing the metabolites and cell population for metabolic engineering
8:55-9:15
Shan Wu, Hubei University
Study of Late nuclear pre-60S ribosomes in Yeast with the help of Cryo-EM
9:15-9:35
Xuan Zhu, Zhejiang Gongshang University
Effect of cobalamin on microbiota and metabolism alternation via an in vitro colonic simulation
9:35-9:55
Qun Wan, Nanjing Agricultural University
Studies of the reaction mechanism of xylanase and the ration design to increase activities in extreme conditions
9:55-10:15
Shaobin Guo, Fuzhou University
Prototype Diverse Synthetic Biological Circuits in a Cell-Free Transcription-Translation System
10:15-10:35
Jiandong Cui, Tianjin University of Science & Technology
Artificial nanocoating: an efficient shielding protection strategy to improve the performance of immobilized enzymes
10:35-10:55
Coffee Break
10:55-11:15
Xiang Zou, Southwest University
System metabolic and process engineering of a yeast-like fungus for polymalic acid and malic acid production
11:15-11:35
Song Yang, Qingdao Agricultural University
Production of 3-hydroxypropionic acid in engineered Methylobacterium extorquens AM1and application of CRISPR interference to rapidly mine a new phytoene desaturase for carotenoid biosynthesis
11:35-11:55
Damao Wang Southwest University
The new technologies for lytic polysaccharide monooxygenases in biomass conversion
Session 5 Bioenergy and the 3rd international Symposium on Zymomonas mobilis
Chair:
Shihui Yang, Hubei University
Katherine M. Pappas, University of Athens
会场: 2楼 汤山
8:30-8:55
Katherine M. Pappas, University of Athens
The SOS response in Zymomonas mobilis
8:55-9:20
Choul-Gyun Lee, Inha University
Omics based in silico analysis of microalgae for biofuel production
9:20-9:40
Xianghui Qi, Jiangsu University
Microbial biosynthesis of functional sugars and alcohols
9:40-10:00
Wenfang Peng, Hubei University
Efficient genome editing in Zymomonas mobilis through exploiting an endogenous Type I-F CRISPR-Cas system
10:00-10:20
Zhiguang Zhu, Tianjin Institute of Industrial Biotechnology, CAS
Sugar-powered enzymatic biofuel cells for bioelectricity generation
10:20-10:40
Coffee Break
10:40-11:05
Xiaoming Bao, Qilu University of Technology
Construction of a novel gene expression system based on RNA polymerase I for large scale screening of high-nucleic acid Saccharomyces cerevisiae strains
11:05-11:30
Shiyou Ding, Michigan State University
Non-destructive imaging of lignin chemistry in plant cell wall
11:30-11:50
Xu Fang, Shandong University
Rational engineering of the ethanol and the chorismate-related pathways in Saccharomyces cerevisiae for tyrosol production
Session 7 Youth Leader Forum
Chair:
Chong Zhang, Tsinghua University
Yao Chen, Nankai University
会场: 2楼 湖熟
8:30-8:50
Feng Li, Tianjin University
Engineering electroactive bacteria by synthetic biology strategies
8:50-9:10
Chunfen Fan, Southwest University
Brassinosteroid overproduction improves poplar biomass quantity and quality to maximize bioethanol yield under green-like process
9:10-9:25
Songwei Wang, Shanghai Jiao Tong University
Cell factory construction based on 4-hydroxybenzoic acid as a precursor in Pseudomonas chlororaphis
9:25-9:40
Lei Wang, Northeast Electric Power University
Identification of a novel piperidine oxidase and rational arrangement of the oxidase into indigoidine pathway by protein scaffold for blue pigment production
9:40-9:55
Gabriel Murillo Morales, Jiangsu University
15-Crown-5, an "impossible" compound derived from partially biodegraded lignin by E. Coli BL21(Lacc) and detected by GC-MS
9:55-10:15
Coffee Break
10:15-10:35
Pan Wu, Hubei University
Preparation of pectate lyase/Cu3(PO4)2 hybrid nanoflower and its catalytic performance as an immobilized enzyme
10:35-10:55
Meng Mei, Hubei University
Engineered Yeast for Highly Efficient Fab Yeast Surface Display by Divergent Promoter, Molecular Chaperon, and ER Retention Optimizations
10:55-11:15
Pankajkumar Waghmare, Shandong University
Construction of efficient and cost-effective cellulase mixtures for lignocellulosic biomass saccharification
11:15-11:30
Shuai You, Jiangsu University of Science and Technology
Synegistic degradation of biomass with xylanase and cellulase by improving xylanase catalytic activity and thermostability using module replacement
Chao Ma, Jiangsu Ocean University
Functional characterization of PLP fold type IV transaminase from Psendonocardia ammonioxydans
Chaoyong Huang, Beijing Institute of Technology
CRISPR-Cas9-assisted native end-joining editing offers a simple strategy for efficient genetic engineering in Escherichia coli
Faying Zhang, Hubei University
Development of a HRV 3C protease-activated T7RNA polymerase (PA RNAP) sensor system for studying protein-protein interaction in E. coli
Fuxing Niu, Zhongshan University
Microbial Metabolic Engineering and Synthetic Biology
Hong Sun, Tianjin University
Modular engineering of Mycobacteria for high-titer production of 9α-hydroxyandrostene 4-ene-3,17-dione from phytosetrols
Hongli Yao, Bozhou University
Research on breeding of high acetic acid producing strain and its metabolism controlling
Huidan Zhang, Qingdao Institute of Bioenergy and Process, Chinese Academy of Sciences
Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina
Jianzhi Zhao, Qilu University of Technology
Metabolic Engineering of Saccharomyces cerevisiae Suitable for the Second-generation Bioethanol Production
Jingling Huang, Qingdao University of Science and Technology
Biosynthesis of natural products of lupulone and humulone in hops
Jinlai Zhang, Tianjin University
High production of fatty alcohols in Yarrowia lipolytica by coordination with glycolysis
Kai Li, Shanghai Jiaotong University
Intracellular redox perturbation in Saccharomyces cerevisiae for improvement of furfural tolerance
Lili Xu，Qilu University of Technology
Construction of an IGR IRES-mediated reporter gene expression system based on RNA polymerase I for large scale screening of high-nucleic acid in Saccharomyces cerevisiae
Lixia Fang, Tianjin University
CRISPRi-omics combined systems metabolic engineering strategy boosts free fatty acids production in Escherichia coli
Luyao Zhao, Beijing Institute of Technology
A novel protein purification strategy mediated by the combination of CipA and Ssp DnaB intein
Nian Liang, Jiangsu University
Cloning and Expression of a new bacterial laccase from Bacillus ligniniphilus L1 DSM 26145T in Escherichia coli to understand enzymatic lignin depolymerization
Qicheng Shi, Nanjing Agricultural College
Expression and Biochemical Function Analysis of Feruloyl Esterase and Its Mutants Derived from Ruminal Anaerobic Fungi
Song Gao, Jiangsu Ocean University
Bacteriophage T4 capsid as a nanocarrier for Peptide-N-Glycosidase F immobilization through self-assembly
Xiangju Wei, East China University of Science and Technology
Biosynthesis of P(3HB-co-LA) from Renewable Carbon Source by Metabolically Engineered Escherichia coli
Xiaoguang Liu, Hebei Normal University For Nationaities
Improved tolerance of Saccharomyces cerevisiae to lignin-derived phenolic acid inhibitors by adaptive laboratory evolution
Yajun Liu, Qingdao Institute of Bioenergy and Process, Chinese Academy of Sciences
Efficient Lignocellulose Conversion to Functional Protein and Oil
Yang Zhang, Xiamen University
Biohydrogen production by the co-culture of Clostridium beijerinckii and Rhodobacter capsulatus with acid resistance