目录产品 » 4-1BBL/TNFSF9, His, Human
4-1BBL/TNFSF9, His, Human

Recombinant 4-1BBL/TNFSF9, His, Human on SDS-PAGE under reducing conditions, the purity is greater than 95%.

4-1BBL/TNFSF9, His, Human

Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4 1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.
Z03653
￥2800

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产品简介
Species Human
Protein Construction
4-1BBL/TNFSF9 (Arg71-Glu254)
Accession # P41273		 Poly-His
N-term C-term
Purity > 95% as analyzed by SDS-PAGE
Endotoxin Level ≤ 1 EU/μg of protein by LAL method
Expression System E. coli
Apparent Molecular Weight 16~20 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized from a 0.2 μm filtered solution in 20 mM Tris-HCl, 150 mM NaCl, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4-7°C and up to 3 months at -20 °C or below. Avoid repeated freeze-thaw cycles.

图例
  • 4-1BBL/TNFSF9, His, Human
    • 4-1BBL/TNFSF9, His, Human

    Recombinant 4-1BBL/TNFSF9, His, Human on SDS-PAGE under reducing conditions, the purity is greater than 95%.


技术背景
Target Background Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4 1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death (AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.
Synonyms Tumor necrosis factor ligand superfamily member 9; 4-1BB ligand; 4-1BBL; TNFSF9

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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