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DNA fragility at topologically associated domain boundaries is promoted by alternative DNA secondary structure and topoisomerase II activity
Authors: Heather M Raimer Young, Pei-Chi Hou, Anna R Bartosik, Naomi D Atkin, Lixin Wang, Zhenjia Wang, Aakrosh Ratan, Chongzhi Zang, Yuh-Hwa Wang
Journal: Nucleic Acids Research
PubMed ID: 38452213
Doi: 10.1093/nar/gkae164
Products & Services: Gene Synthesis   
MiR-326 sponges TET2 triggering imbalance of Th17/Treg differentiation to exacerbate pyroptosis of hepatocytes in concanavalin A-induced autoimmune hepatitis
Authors: Genglin Zhang, Sensen Wu, Guangtao Xia
Journal: Hepatology
PubMed ID: 38043702
Doi: 10.1016/j.aohep.2023.101183
Products & Services: Codon Optimization   
Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology
Authors: Brendan Miller, Su-Jeong Kim, Kevin Cao, Hemal H Mehta, Neehar Thumaty, Hiroshi Kumagai, Tomomitsu Iida, Cassandra McGill, Christian J Pike, Kamila Nurmakova, Zachary A Levine, Patrick M Sullivan, Kelvin Yen, Nilüfer Ertekin-Taner, Gil Atzmon, Nir Barzilai, Pinchas Cohen
Journal: Cell
PubMed ID: 38520065
Doi: 10.1111/acel.14153
Products & Services: Gene Synthesis   
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins
Authors: Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
Journal: Nature
PubMed ID: 38509117
Doi: 10.1038/s41467-024-46644-7
Products & Services: Plasmid DNA Preparation   
Integrative high-throughput enhancer surveying and functional verification divulges a YY2-condensed regulatory axis conferring risk for osteoporosis
Authors: Xiao-Feng Chen, Yuan-Yuan Duan, Ying-Ying Jia, Qian-Hua Dong, Wei Shi, Yan Zhang, Shan-Shan Dong, Meng Li, Zhongbo Liu, Fei Chen, Xiao-Ting Huang, Ruo-Han Hao, Dong-Li Zhu, Rui-Hua Jing, Yan Guo, Tie-Lin Yang
Journal: Cell Genom
PubMed ID: 38335956
Doi: 1016/j.xgen.2024.100501
Products & Services: Gene Synthesis   
Development of a colloidal gold immunochromatographic strip for rapid detection of avian coronavirus infectious bronchitis virus
Authors: Chang-Run Zhao, Li-Ting Lin, Jin-Wen Tang, Yu Zhang, Wen Zhang, Ji-Ming Chen, Ping Wei, Teng Huang, Tian-Chao Wei, Mei-Lan Mo
Journal: Poult Sci
PubMed ID: 38574460
Doi: 10.1016/j.psj.2024.103648.
Endothelial β-catenin upregulation and Y142 phosphorylation drive diabetic angiogenesis via upregulating KDR/HDAC9
Authors: Zhenfeng Chen, Bingqi Lin, Xiaodan Yao, Jie Weng, Jinlian Liu, Qi He, Ke Song, Chuyu Zhou, Zirui Zuo, Xiaoxia Huang, Zhuanhua Liu, Qiaobing Huang, Qiulin Xu, Xiaohua Guo
Journal: Cell Commun Signal
PubMed ID: 38491522
Doi: 10.1186/s12964-024-01566-1
Products & Services: Recombinant Proteins   
Reactive Oxygen Species-Responsive Nanoparticles Toward Extracellular Matrix Normalization for Pancreatic Fibrosis Regression
Authors: Liang Qi, Bo-Wen Duan, Hui Wang, Yan-Jun Liu, Han Han, Meng-Meng Han, Lei Xing, Hu-Lin Jiang, Stephen J Pandol, Ling Li
Journal: Adv Sci (Weinh)
PubMed ID: 38483920
Doi: 10.1002/advs.202401254
Products & Services: Catalog Antibody   
Highly sensitive spatial transcriptomics using FISHnCHIPs of multiple co-expressed genes
Authors: Xinrui Zhou , Wan Yi Seow, Norbert Ha, Teh How Cheng, Lingfan Jiang, Jeeranan Boonruangkan, Jolene Jie Lin Goh, Shyam Prabhakar, Nigel Chou, Kok Hao Chen Affiliations expand
Journal: Nat Commun
PubMed ID: 38491027
Doi: s41467-024-46669-y
Products & Services: Gene Synthesis   
Bacillus cereus cereolysin O induces pyroptosis in an undecapeptide-dependent manner
Authors: Yujian Wang, Jingchang Luo, Xiaolu Guan , Yan Zhao , Li Sun
Journal: Cell Death Discov
PubMed ID: 38458999
Doi: 10.1038/s41420-024-01887-7
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