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CriSNPr, a single interface for the curated and de novo design of gRNAs for CRISPR diagnostics using diverse Cas systems

Authors: Asgar H Ansari, Manoj Kumar, Sajal Sarkar, Souvik Maiti, Debojyoti Chakraborty

Journal: Elife

PubMed ID: 36752591

Doi: 10.7554/eLife.77976

Products & Services: Proteins, Expression, Isolation and Analysis

Dynamic states of eIF6 and SDS variants modulate interactions with uL14 of the 60S ribosomal subunit

Authors: Jonah Elliff, Aparna Biswas, Poonam Roshan, Sahiti Kuppa, Angela Patterson, Jenna Mattice, Mathivanan Chinnaraj, Ryan Burd, Sarah E Walker, Nicola Pozzi, Edwin Antony, Brian Bothner, Sofia Origanti

Journal: Nucleic Acids Res

PubMed ID: 36651285

Doi: 10.1093/nar/gkac1266

Products & Services: Proteins, Expression, Isolation and Analysis

KLF3 Transcription Activates WNT1 and Promotes the Growth and Metastasis of Gastric Cancer via Activation of the WNT/β-Catenin Signaling Pathway

Authors: Ying Li, Yu Wang, Qinguang Zou, Shouqing Li, Fan Zhang

Journal: Lab Invest

PubMed ID: 36827869

Doi: 10.1016/j.labinv.2023.100078

Products & Services: Proteins, Expression, Isolation and Analysis

Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients

Authors: Romain Rouet, Jake Y Henry, Matt D Johansen, Meghna Sobti, Harikrishnan Balachandran, David B Langley, Gregory J Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L Burnett, Simon H J Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C Goodnow, Stuart G Turville, William D Rawlinson, Rowena A Bull, Alastair G Stewart, Philip M Hansbro, Daniel Christ

Journal: Nat Commun

PubMed ID: 36755042

Doi: 10.1038/s41467-023-36295-5

Products & Services: Proteins, Expression, Isolation and Analysis

Barrier properties of Nup98 FG phases ruled by FG motif identity and inter-FG spacer length

Authors: Sheung Chun Ng, Abin Biswas, Trevor Huyton, Jürgen Schünemann, Simone Reber, Dirk Görlich

Journal: Nat Commun

PubMed ID: 36765044

Doi: 10.1038/s41467-023-36331-4

Products & Services: Proteins, Expression, Isolation and Analysis

Safety and Immunogenicity of Betuvax-CoV-2, an RBD-Fc-Based SARS-CoV-2 Recombinant Vaccine: Preliminary Results of the First-in-Human, Randomized, Double-Blind, Placebo-Controlled Phase I/II Clinical Trial

Authors: Aleksandr V Kudriavtsev, Anna V Vakhrusheva, Nickolay A Kryuchkov, Maria E Frolova, Konstantin A Blagodatskikh, Taras V Ivanishin, Milana Djonovic, Ekaterina A Romanovskaya-Romanko, Anton N Kovalenko, Dmitry A Lioznov, Tatiana G Zubkova, Svetlana V Teplykh, Rodion A Oseshnyuk, Marina A Stukova, Artur A Isaev, Igor V Krasilnikov

Journal: Vaccines (Basel)

PubMed ID: 36851204

Doi: 10.3390/vaccines11020326

Products & Services: Proteins, Expression, Isolation and Analysis

Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine

Authors: Thayne H Dickey, Richi Gupta, Holly McAleese, Tarik Ouahes, Sachy Orr-Gonzalez, Rui Ma, Olga Muratova, Nichole D Salinas, Jen C C Hume, Lynn E Lambert, Patrick E Duffy, Niraj H Tolia

Journal: npj Vaccines

PubMed ID: 36808125

Doi: 10.1038/s41541-023-00619-9

Products & Services: Proteins, Expression, Isolation and Analysis

Structure and dynamics of the EGFR/HER2 heterodimer

Authors: Xue Bai, Pengyu Sun, Xinghao Wang, Changkun Long, Shuyun Liao, Song Dang, Shangshang Zhuang, Yongtao Du, Xinyi Zhang, Nan Li, Kangmin He, Zhe Zhang

Journal: Cell Discov

PubMed ID: 36781849

Doi: 10.1038/s41421-023-00523-5

Products & Services: Proteins, Expression, Isolation and Analysis

Acid-Responsive Immune-Enhancing Chitosan Formulation Capable of Transforming from Particle Stabilization to Polymer Chain Stabilization

Authors: Yongjuan Zou, Xiaoxuan Liu, Qiuting Chen, Hiroyuki Oku, Guanghui Ma, Jie Wu

Journal: ACS Appl Mater Interfaces

PubMed ID: 36825996

Doi: 10.1021/acsami.2c17505

Products & Services: Proteins, Expression, Isolation and Analysis

Cas12a-based one-pot SNP detection with high accuracy

Authors: Hong-Xia Zhang, Caixiang Zhang, Shuhan Lu, Xiaohan Tong, Kun Zhang, Hao Yin, Ying Zhang