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Pathological Hyperinsulinemia and Hyperglycemia in the Impaired Glucose Tolerance Stage Mediate Endothelial Dysfunction Through miR-21, PTEN/AKT/eNOS, and MARK/ET-1 Pathways
Authors: Ran Liu, Shilin Guan, Zhongai Gao, Jingyu Wang, Jie Xu, Zhaohu Hao, Yi Zhang, Shaohua Yang, Zhenhong Guo, Juhong Yang, Hailin Shao, Baocheng Chang
Journal: Front Endocrinol (Lausanne)
PubMed ID: 33967958
Doi: 10.3389/fendo.2021.644159
Products & Services: Recombinant Proteins   
In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure
Authors: Peter Gargalovic, Pancras Wong, Joelle Onorato, Heather Finlay, Tao Wang, Mujing Yan, Earl Crain, Stéphane St-Onge, Madeleine Héroux, Michel Bouvier, Carrie Xu, Xue-Qing Chen, Claudia Generaux, Michael Lawrence, Ruth Wexler, David Gordon
Journal: Circ Heart Fail
PubMed ID: 33663236
Doi: 10.1161/CIRCHEARTFAILURE.120.007351
Products & Services: Recombinant Proteins   
By inhibiting ADCY5, miR-18a-3p promotes osteoporosis and possibly contributes to spinal fracture
Authors: Lei Wang, Junli Dong, Jun Ma, Qin Lu, Ben Shan, Tingting Han, Peng Xie, Xiaohua Zuo
Journal: Biochem Biophys Res Commun
PubMed ID: 33684620
Doi: 10.1016/j.bbrc.2021.02.118
Products & Services: Recombinant Proteins   
Inhibition of P110α and P110δ catalytic subunits of PI3 kinase reverses impaired arterial healing after injury in hypercholesterolemic male mice
Authors: Pinaki Chaudhuri, Andrew H Smith, Linda M Graham, Michael A Rosenbaum
Journal: Am J Physiol Cell Physiol
PubMed ID: 33689479
Doi: 10.1152/ajpcell.00600.2020
Products & Services: Recombinant Proteins   
Obtusifolin, an Anthraquinone Extracted from (L) HSIrwin & Barneby, Reduces Inflammation in a Mouse Osteoarthritis Model
Authors: Jiho Nam, Dong-Won Seol, Choong-Gu Lee, Gabbine Wee, Siyoung Yang, Cheol-Ho Pan
Journal: Pharmaceuticals (Basel)
PubMed ID: 33802005
Doi: 10.3390/ph14030249
Products & Services: Recombinant Proteins   
Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy
Authors: Chenglong Liu, Feilong Zhou, Ziqin Yan, Lian Shen, Xichen Zhang, Fenglian He, Heng Wang, Xiaojie Lu, Ker Yu, Yujun Zhao, Di Zhu
Journal: Br J Pharmacol
PubMed ID: 33768523
Doi: 10.1111/bph.15457
Products & Services: Recombinant Proteins   
Immunocompetent Human 3D Organ-Specific Hormone-Responding Vaginal Mucosa Model of HIV-1 Infection
Authors: Ingrid Saba, Corinne Barat, Stéphane Chabaud, Nolan Reyjon, Maude Leclerc, Weronika Jakubowska, Hazem Orabi, Asmaa Lachhab, Martin Pelletier, Michel J Tremblay, Stéphane Bolduc
Journal: Tissue Eng Part C Methods
PubMed ID: 33573474
Doi: 10.1089/ten.TEC.2020.0333
Products & Services: Recombinant Proteins   
A human epidermal growth factor receptor 3/heregulin interaction inhibitor aptamer discovered using SELEX
Authors: Takumi Yokoyama, Takehiro Ando, Rina Iwamoto, Daisuke Fuji, Mizuki Yamamoto, Takashi Kawakami
Journal: Biochem Biophys Res Commun
PubMed ID: 33770580
Doi: 10.1016/j.bbrc.2021.03.076
Products & Services: Recombinant Proteins   
STAMP2 Expression Mediated by Cytokines Attenuates Their Growth-Limiting Effects in Prostate Cancer Cells
Authors: Nicklas Pihlstrøm, Yang Jin, Zeynep Nenseth, Omer F Kuzu, Fahri Saatcioglu
Journal: Cancers (Basel)
PubMed ID: 33808059
Doi: 10.3390/cancers13071579
Products & Services: Recombinant Proteins   
Optimization of Zika DNA vaccine by delivery systems
Authors: Yun Ha Lee, Heeji Lim, Jung-Ah Lee, Su Hwan Kim, Yun-Ho Hwang, Hyun Ju In, Mi Young Kim, Gyung Tae Chung
Journal: Virology
PubMed ID: 33780719
Doi: 10.1016/j.virol.2021.03.005
Products & Services: Recombinant Proteins   

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