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Engineering CAR-T cells to activate small-molecule drugs in situ
Authors: Thomas J Gardner, J Peter Lee, Christopher M Bourne, Dinali Wijewarnasuriya, Nihar Kinarivala, Keifer G Kurtz, Broderick C Corless, Megan M Dacek, Aaron Y Chang, George Mo, Kha M Nguyen, Renier J Brentjens, Derek S Tan, David A Scheinberg
Journal: Nat Chem Biol
PubMed ID: 34969970
Doi: 10.1038/s41589-021-00932-1
Silencing an E3 Ubiquitin Ligase Gene OsJMJ715 Enhances the Resistance of Rice to a Piercing-Sucking Herbivore by Activating ABA and JA Signaling Pathways
Authors: Yuebai Zhang , Mengting Chen , Shuxing Zhou , Yonggen Lou , Jing Lu
Journal: Int J Mol Sci
PubMed ID: 34884830
Doi: 10.3390/ijms222313020
MON-2, a Golgi protein, mediates autophagy-dependent longevity in
Authors: Yoonji Jung, Murat Artan, Nari Kim, Jeonghun Yeom, Ara B Hwang, Dae-Eun Jeong, Özlem Altintas, Keunhee Seo, Mihwa Seo, Dongyeop Lee, Wooseon Hwang, Yujin Lee, Jooyeon Sohn, Eun Ji E Kim, Sungeun Ju, Seong Kyu Han, Hyun-Jun Nam, Linnea Adams, Youngjae Ryu, Dong Jin Moon, Chanhee Kang, Joo-Yeon Yoo, Sang Ki Park, Chang Man Ha, Malene Hansen, Sanguk Kim, Cheolju Lee, Seung-Yeol Park, Seung-Jae V Lee
Journal: Sci Adv
PubMed ID: 34860542
Doi: 10.1126/sciadv.abj8156
The protective effects of S14G-humanin (HNG) against streptozotocin (STZ)-induced cardiac dysfunction
Authors: Xiaopan Chen, Chuan Yun, Hailong Zheng, Xu Chen, Qianfei Han, Hua Pan, Yang Wang, Jianghua Zhong
Journal: Bioengineered
PubMed ID: 34506248
Doi: 10.1080/21655979.2021.1964894
Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex
Authors: Luke F Pennington, Pascal Gasser, Silke Kleinboelting, Chensong Zhang, Georgios Skiniotis, Alexander Eggel, Theodore S Jardetzky
Journal: Nat Commun
PubMed ID: 34862384
Doi: 10.1038/s41467-021-27397-z
NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy
Authors: Emma L Lewis, Rong Xu, Jean-Christophe Beltra, Shin Foong Ngiow, Jordana Cohen, Rahul Telange, Alexander Crane, Deirdre Sawinski, E John Wherry, Paige M Porrett
Journal: J Exp Med
PubMed ID: 34882194
Doi: 10.1084/jem.20201599
Biomaterial-mediated presentation of wnt5a mimetic ligands enhances chondrogenesis and metabolism of stem cells by activating non-canonical Wnt signaling
Authors: Yingrui Deng, Xiaoting Zhang, Rui Li, Zhuo Li, Boguang Yang, Peng Shi, Honglu Zhang, Chunming Wang, Chunyi Wen, Gang Li, Liming Bian
Journal: Biomaterials
PubMed ID: 34959028
Doi: 10.1016/j.biomaterials.2021.121316
Development of a high-throughput RT-PCR based viral infectivity assay for monitoring the stability of a replicating recombinant Lymphocytic Choriomeningitis viral vector
Authors: Vineet Gupta, Lorena R Antunez, Soraia Saleh-Birdjandi, Ozan S Kumru, Richard Pospisil, Anders Lilja, Gerhard Fuhrmann, Lee Smith, David B Volkin, Sangeeta B Joshi
Journal: J Virol Methods
PubMed ID: 34954306
Doi: 10.1016/j.jviromet.2021.114440
Direct visualization by FRET-FLIM of a putative mechanosome complex involving Src, Pyk2 and MBD2 in living MLO-Y4 cells
Authors: Richard N Day, Kathleen H Day, Fredrick M Pavalko
Journal: PLoS ONE
PubMed ID: 34941939
Doi: 10.1371/journal.pone.0261660
ProtSeq: Toward high-throughput, single-molecule protein sequencing via amino acid conversion into DNA barcodes
Authors: Jessica M Hong, Michael Gibbons, Ali Bashir, Diana Wu, Shirley Shao, Zachary Cutts, Mariya Chavarha, Ye Chen, Lauren Schiff, Mikelle Foster, Victoria A Church, Llyke Ching, Sara Ahadi, Anna Hieu-Thao Le, Alexander Tran, Michelle Dimon, Marc Coram, Brian Williams, Phillip Jess, Marc Berndl, Annalisa Pawlosky
Journal: iScience
PubMed ID: 35005536
Doi: 10.1016/j.isci.2021.103586

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