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Staphylococcus aureus functional amyloids catalyze degradation of β-lactam antibiotics
Authors: Elad Arad , Kasper B Pedersen , Orit Malka, Sisira Mambram Kunnath , Nimrod Golan , Polina Aibinder , Birgit Schiøtt , Hanna Rapaport, Meytal Landau , Raz Jelinek
Journal: Nat Commun .
PubMed ID: 38081813
Doi: s41467-023-43624-1
Products & Services: Peptide Synthesis   
Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate
Authors: Liyang Du , Qinwei Zhu & Zhonghui Lin
Journal: The EMBO Journal
Doi: 10.1038/s44318-023-00017-w
Products & Services: Gene Synthesis   
Structural dynamics of the CROPs domain control stability and toxicity of Paeniclostridium sordellii lethal toxin
Authors: Yao Zhou, Xiechao Zhan , Jianhua Luo, Diyin Li , Ruoyu Zhou , Jiahao Zhang , Zhenrui Pan , Yuanyuan Zhang , Tianhui Jia , Xiaofeng Zhang , Yanyan Li , Liang Tao
Journal: Nat Commun .
PubMed ID: 38114525
Doi: 10.1038/s41467-023-44169-z
Products & Services: Codon Optimization   
Structural analysis and functional evaluation of the disordered ß–hexosyltransferase region from Hamamotoa (Sporobolomyces) singularis
Authors: Suzanne F Dagher, Asmita Vaishnav, Christopher B Stanley, Flora Meilleur, Brian F P Edwards , José M Bruno-Bárcena
Journal: Front Bioeng Biotechnol
PubMed ID: 38162180
Doi: 10.3389/fbioe.2023.1291245
Products & Services: Gene Synthesis   
A functional and structural comparative analysis of Large Tumor Antigens reveals evolution of different importin α-dependent nuclear localization signals
Authors: Emily M Cross, Nasim Akbari, Hanieh Ghassabian, Mikayla Hoad, Silvia Pavan, Daryl Ariawan, Camilla M Donnelly, Enrico Lavezzo, Gayle F Petersen, Jade K Forwood, Gualtiero Alvisi
Journal: Protein Sci
PubMed ID: 38108201
Doi: 10.1002/pro.4876
Products & Services: Molecular Biology Reagents   
Choosing the right mouse model: comparison of humanized NSG and NBSGW mice for in vivo HSC gene therapy
Authors: Seunga Choo, Carl B Wolf, Heather M Mack, Mitchell J Egan, Hans-Peter Kiem, Stefan Radtke
Journal: Blood Adv
PubMed ID: 38113461
Doi: 10.1182/bloodadvances.2023011371
Products & Services: Molecular Biology Reagents   
Secretory carrier-associated membrane protein 5 regulates cell-surface targeting of T-type calcium channels
Authors: Emilio R Mustafá, Konstantin Weiß, Norbert Weiss
Journal: Channels (Austin)
PubMed ID: 37389974
Doi: 10.1080/19336950.2023.2230776
Products & Services: Gene Synthesis   
Safety and efficacy of a novel anti-CD19 chimeric antigen receptor T cell product targeting a membrane-proximal domain of CD19 with fast on- and off-rates against non-Hodgkin lymphoma: a first-in-human study
Authors: Yunlin Zhang, Ruchi P Patel, Ki Hyun Kim, Hyungwoo Cho, Jae-Cheol Jo, Seong Hyun Jeong, Sung Yong Oh, Yoon Seok Choi, Sung Hyun Kim, Ji Hyun Lee, Mathew Angelos, Puneeth Guruprasad, Ivan Cohen, Ositadimma Ugwuanyi, Yong Gu Lee, Raymone Pajarillo, Jong Hyun Cho, Alberto Carturan, Luca Paruzzo, Guido Ghilardi, Michael Wang, Soohwan Kim, Sung-Min Kim, Hyun-Jong Lee, Ji-Ho Park, Leiguang Cui, Tae Bum Lee, In-Sik Hwang, Young-Ha Lee, Yong-Jun Lee, Patrizia Porazzi, Dongfang Liu, Yoon Lee, Jong-Hoon Kim, Jong-Seo Lee, Dok Hyun Yoon, Junho Chung, Marco Ruella
Journal: Mol Cancer
PubMed ID: 38066564
Doi: 10.1186/s12943-023-01886-9
Products & Services: Recombinant Proteins   
N6-methyladenosine methylation analysis of long noncoding RNAs and mRNAs in 5-FU-resistant colon cancer cells
Authors: Jie Lai, Zhiyong Zhou, Kan Hu, HongLong Yu, Xingyao Su, Xiaoqiang Niu, Huizi Li, Shengxun Mao
Journal: Epigenetics
PubMed ID: 38145548
Doi: 10.1080/15592294.2023.2298058
Products & Services: Custom DNA/RNA Oligos   
Combinatorial design of ionizable lipid nanoparticles for muscle-selective mRNA delivery with minimized off-target effects
Authors: Jingan Chen, Yue Xu, Muye Zhou, Shufen Xu, Andrew James Varley, Alex Golubovic, Rick Xing Ze Lu, Kevin Chang Wang, Mina Yeganeh, Daniel Vosoughi, Bowen Li
Journal: Proc Natl Acad Sci U S A
PubMed ID: 38060560
Doi: 10.1073/pnas.2309472120
Products & Services: Molecular Biology Reagents   

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