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Flavivirus genome recoding by codon optimisation confers genetically stable in vivo attenuation in both mice and mosquitoes
Authors: Wei-Xin Chin, Hao Yuin Kong, Isabelle Xin Yu Zhu, Zi Yun Teo, Regina Faruk, Regina Ching Hua Lee, Si Xian Ho, Zhen Qin Aw, Bowen Yi, Xin Jun Hou, Antson Kiat Yee Tan, Thinesshwary Yogarajah, Roland G Huber, Yu Cai, Yue Wan, Justin Jang Hann Chu
Journal: PLoS Pathog
PubMed ID: 37883598
Doi: 10.1371/journal.ppat.1011753
Products & Services: Molecular Biology Reagents   
Tetravalent SARS-CoV-2 S1 subunit protein vaccination elicits robust humoral and cellular immune responses in SIV-infected rhesus macaque controllers
Authors: Muhammad S Khan, Eun Kim, Quentin Le Hingrat, Adam Kleinman, Alessandro Ferrari, Jose C Sammartino, Elena Percivalle, Cuiling Xu, Shaohua Huang, Thomas W Kenniston, Irene Cassaniti, Fausto Baldanti, Ivona Pandrea, Andrea Gambotto, Cristian Apetrei
Journal: MBio
PubMed ID: 37830800
Doi: 10.1128/mbio.02070-23
Products & Services: Molecular Biology Reagents   
Improved Stability and Manufacturability of Nucleocapsid Antigens for SARS-CoV2 Diagnostics through Protein Engineering
Authors: Esha Shukla, Lipsa Choudhury, Saurabh Rastogi, Arshmeet Chawla, Sanghati Bhattacharya, Umesh Kaushik, Manan Mittal, Anurag Singh Rathore, Gaurav Pandey
Journal: Biomolecules
PubMed ID: 37892206
Doi: 10.3390/biom13101524
Products & Services: Custom Vector Construction   
Proteomic Analysis Reveals a PLK1-Dependent G2/M Degradation Program and Links PKA-AKAP2 to Cell Cycle Control
Authors: Ryan D Mouery, Carolyn Hsu, Thomas Bonacci, Derek L Bolhuis, Xianxi Wang, Christine A Mills, E Drew Toomer, Owen G Canterbury, Kevin C Robertson, Timothy B Branigan, Nicholas G Brown, Laura E Herring, Michael J Emanuele
Journal: biorxiv
PubMed ID: 37873169
Doi: 10.1101/2023.10.11.561963
Products & Services: Custom Vector Construction   
Cryo-EM structure of severe fever with thrombocytopenia syndrome virus
Authors: Shouwen Du, Ruchao Peng, Wang Xu, Xiaoyun Qu, Yuhang Wang, Jiamin Wang, Letian Li, Mingyao Tian, Yudong Guan, Jigang Wang, Guoqing Wang, Hao Li, Lingcong Deng, Xiaoshuang Shi, Yidan Ma, Fengting Liu, Minhua Sun, Zhengkai Wei, Ningyi Jin, Wei Liu, Jianxun Qi, Quan Liu, Ming Liao, Chang Li
Journal: Nat Commun
PubMed ID: 37816705
Doi: 10.1038/s41467-023-41804-7
Products & Services: Peptide Synthesis   
Specific Nucleotides in the Common Region of the Begomovirus Tomato Rugose Mosaic Virus (ToRMV) Are Responsible for the Negative Interference over Tomato Severe Rugose Virus (ToSRV) in Mixed Infection
Authors: Angélica M Nogueira, Tarsiane M C Barbosa, Ayane F F Quadros, Anelise F Orílio, Marcela C J Bigão, César A D Xavier, Camila G Ferro, Francisco Murilo Zerbini
Journal: Viruses
PubMed ID: 37896851
Doi: 10.3390/v15102074
Products & Services: Recombinant Proteins   
Lactate promotes intracellular replication and systemic infection via driving macrophage M2 polarization
Authors: Xinyue Wang, Bin Yang, Shuangshuang Ma, Xiaolin Yan, Shuai Ma, Hongmin Sun, Yuyang Sun, Lingyan Jiang
Journal: Microbiol Spectr
PubMed ID: 37796020
Doi: 10.1128/spectrum.02253-23
Products & Services: PCR Cloning and Subcloning   
Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute
Authors: Xiaopan Gao , Kun Shang , Kaixiang Zhu , Linyue Wang , Zhixia Mu , Xingke Fu , Xia Yu , Bo Qin , Hongtao Zhu , Wei Ding , Sheng Cui
Journal: Nature .
PubMed ID: 37783228
Doi: 10.1038/s41586-023-06665-6
Products & Services: DNA Sequencing   
Plant-Based Meat Analogues Weaken Gastrointestinal Digestive Function and Show Less Digestibility Than Real Meat in Mice
Authors: Yunting Xie , Linlin Cai , Zhiji Huang , Kai Shan , Xinglian Xu , Guanghong Zhou , Chunbao Li
Journal: J Agric Food Chem .
PubMed ID: 36070521
Doi: 10.1021/acs.jafc.2c04246
Products & Services: Gene Synthesis   
Single Amino Acid Mutation Decouples Photochemistry of the BLUF Domain from the Enzymatic Function of OaPAC and Drives the Enzyme to a Switched-on State
Authors: Jinnette Tolentino Collado, Emoke Bodis, Jonatan Pasitka, Mihaly Szucs, Zsuzsanna Fekete, Nikolett Kis-Bicskei, Elek Telek, Kinga Pozsonyi, Sofia M Kapetanaki, Greg Greetham, Peter J Tonge, Stephen R Meech, Andras Lukacs
Journal: J Mol Biol
PubMed ID: 37827329
Doi: 10.1016/j.jmb.2023.168312

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