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页码: 69/4919 每页显示数量

Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding

Authors: Ladan Khodaparast, Laleh Khodaparast, Guiqin Wu, Emiel Michiels, Rodrigo Gallardo, Bert Houben, Teresa Garcia, Matthias De Vleeschouwer, Meine Ramakers, Hannah Wilkinson, Ramon Duran-Romaña, Johan Van Eldere, Frederic Rousseau, Joost Schymkowitz

Journal: Nat Commun

PubMed ID: 37689716

Doi: 10.1038/s41467-023-41191-z

Products & Services: Peptide Synthesis

CST2 is activated by RUNX1 and promotes pancreatic cancer progression by activating PI3K/AKT pathway

Authors: Rongwen Ou, Chengjie Lin, Youting Chen

Journal: Arch Biochem Biophys

PubMed ID: 37722526

Doi: 10.1016/j.abb.2023.109760

Products & Services: Custom RNAi Services

Isofagomine inhibits multiple TcdB variants and protects mice from induced mortality

Authors: Ashleigh S Paparella, Isabella Brew, Huynh A Hong, William Ferriera, Simon Cutting, Farah Lamiable-Oulaidi, Michael Popadynec, Peter C Tyler, Vern L Schramm

Journal: biorxiv

PubMed ID: 37781587

Doi: 10.1101/2023.09.19.558375

Products & Services: Combinatorial DNA Libraries

A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses

Authors: Sneha Vishwanath, George William Carnell, Matteo Ferrari, Benedikt Asbach, Martina Billmeier, Charlotte George, Maria Suau Sans, Angalee Nadesalingam, Chloe Qingzhou Huang, Minna Paloniemi, Hazel Stewart, Andrew Chan, David Arthur Wells, Patrick Neckermann, David Peterhoff, Sebastian Einhauser, Diego Cantoni, Martin Mayora Neto, Ingo Jordan, Volker Sandig, Paul Tonks, Nigel Temperton, Simon Frost, Katharina Sohr, Maria Teresa Lluesma Ballesteros, Farzad Arbabi, Johannes Geiger, Christian Dohmen, Christian Plank, Rebecca Kinsley, Ralf Wagner, Jonathan Luke Heeney

Journal: Nat Biomed Eng

PubMed ID: 37749309

Doi: 10.1038/s41551-023-01094-2

Products & Services: Proteins, Expression, Isolation and Analysis

A mechanism that ensures non-selective cytoplasm degradation by autophagy

Authors: Tetsuya Kotani, Yuji Sakai, Hiromi Kirisako, Chika Kakuta, Soichiro Kakuta, Yoshinori Ohsumi, Hitoshi Nakatogawa

Journal: Nat Commun

PubMed ID: 37726301

Doi: 10.1038/s41467-023-41525-x

Products & Services: Gene Synthesis

Host Interactions with Engineered T-cell Micropharmacies

Authors: Christopher M Bourne, Patrick Wallisch, Megan M Dacek, Thomas J Gardner, Stephanie Pierre, Kristen Vogt, Broderick C Corless, Mamadou A Bah, Jesus E Romero-Pichardo, Angel Charles, Keifer G Kurtz, Derek S Tan, David A Scheinberg

Journal: Cancer Immunol Res

PubMed ID: 37379366

Doi: 10.1158/2326-6066.CIR-22-0879

Products & Services: Molecular Biology Reagents

CDK10 suppresses metastasis of lung adenocarcinoma through inhibition of the ETS2/c-Raf/p-MEK/p-ERK signaling loop

Authors: Xiujuan Zhang, Yu Zhao, Ruzetuoheti Yiminniyaze, Ning Zhu, Yuanyuan Zhang, Gulinuer Wumaier, Jingwen Xia, Liang Dong, Daibing Zhou, Jing Wang, Chengwei Li, Youzhi Zhang, Shengqing Li

Journal: Mol Carcinog

PubMed ID: 37737453

Doi: 10.1002/mc.23636

Products & Services: Molecular Biology Reagents

A Proteorhodopsin-Related Photosensor Expands the Repertoire of Structural Motifs Employed by Sensory Rhodopsins

Authors: Maryam Saliminasab, Yoichi Yamazaki, Alyssa Palmateer, Andrew Harris, Luiz Schubert, Pit Langner, Joachim Heberle, Ana-Nicoleta Bondar, Leonid S Brown

Journal: J Phys Chem B

PubMed ID: 37694950

Doi: 10.1021/acs.jpcb.3c04032

Products & Services: Mutant Libraries

RIG-I promotes immune evasion of colon cancer by modulating PD-L1 ubiquitination

Authors: Yangyang Zhang # 1, Lingxiu Zeng # 1, Meng Wang 1, Zhenwei Yang 1, Hailin Z 1, Liping Gao , Ranran Zhang , Jialong Liu , Wenqing Shan , Ying Chang ,Lan Liu , Qiu Zhao , Yong Li , Jing Liu

Journal: J Immunother Cancer .

PubMed ID: 37758653

Doi: 10.1136/jitc-2023-007313

Products & Services: Catalog Peptides

Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A

Authors: Zhiheng Deng, Huasong Ai, Maoshen Sun, Zebin Tong, Yunxiang Du, Qian Qu, Liying Zhang, Ziyu Xu, Shixian Tao, Qiang Shi, Jia-Bin Li, Man Pan, Lei Liu

Journal: Mol Cell

PubMed ID: 37633270

Doi: 10.1016/j.molcel.2023.08.001

Products & Services: Proteins, Expression, Isolation and Analysis

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