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CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia

Authors: Omer Gilan, Laure Talarmain, Charles C Bell, Daniel Neville, Kathy Knezevic, Daniel T Ferguson, Marion Boudes, Yih-Chih Chan, Chen Davidovich, Enid Y N Lam, Mark A Dawson

Journal: Nat Struct Mol Biol

PubMed ID: 37679565

Doi: 10.1038/s41594-023-01087-4

Products & Services: Proteins, Expression, Isolation and Analysis

Differential regulatory control of curli (csg) gene expression in Salmonella enterica serovar Typhi requires more than a functional CsgD regulator

Authors: Camille Ou, Charles M Dozois, France Daigle

Journal: Sci Rep

PubMed ID: 37689734

Doi: 10.1038/s41598-023-42027-y

Products & Services: Monoclonal Antibody Services

Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease

Authors: Yugendar R Alugubelli, Jing Xiao, Kaustav Khatua, Sathish Kumar, Yuying Ma, Xinyu R Ma, Veerabhadra R Vulupala, Sandeep R Atla, Lauren Blankenship, Demonta Coleman, Benjamin W Neuman, Wenshe Ray Liu, Shiqing Xu

Journal: biorxiv

PubMed ID: 37808777

Doi: 10.1101/2023.09.29.560163

Products & Services: Proteins, Expression, Isolation and Analysis

mRNA vaccines encoding fusion proteins of monkeypox virus antigens protect mice from vaccinia virus challenge

Authors: Fujun Hou, Yuntao Zhang, Xiaohu Liu, Yanal M Murad, Jiang Xu, Zhibin Yu, Xianwu Hua, Yingying Song, Jun Ding, Hongwei Huang, Ronghua Zhao, William Jia, Xiaoming Yang

Journal: Nat Commun

PubMed ID: 37739969

Doi: 10.1038/s41467-023-41628-5

Products & Services: Codon Optimization

Development of an anti-SARS-CoV-2 monoclonal antibody panel and its applicability as a reagent in high-throughput fluorescence reduction neutralization and immunohistochemistry assays

Authors: Gabriela M Coelho, Allan H D Cataneo, Sonia M Raboni, Meri B Nogueira, Caroline B Vaz de Paula, Ana C S F Almeida, Vanessa Z Rogerio, Nilson T Zanchin, Lucia de Noronha, Camila Zanluca, Claudia N Duarte Dos Santos

Journal: J Med Virol

PubMed ID: 37750235

Doi: 10.1002/jmv.29111

Products & Services: Proteins, Expression, Isolation and Analysis

Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models

Authors: Debashis Dutta, Malabendu Jana, Ramesh Kumar Paidi, Moumita Majumder, Sumita Raha, Sridevi Dasarathy, Kalipada Pahan

Journal: J Clin Invest

PubMed ID: 37552543

Doi: 10.1172/JCI161987

Products & Services: Proteins, Expression, Isolation and Analysis

A Type II-B Cas9 nuclease with minimized off-targets and reduced chromosomal translocations in vivo

Authors: Burcu Bestas, Sandra Wimberger, Dmitrii Degtev, Alexandra Madsen, Antje K Rottner, Fredrik Karlsson, Sergey Naumenko, Megan Callahan, Julia Liz Touza, Margherita Francescatto, Carl Ivar Möller, Lukas Badertscher, Songyuan Li, Silvia Cerboni, Niklas Selfjord, Elke Ericson, Euan Gordon, Mike Firth, Krzysztof Chylinski, Amir Taheri-Ghahfarokhi, Mohammad Bohlooly-Y, Mike Snowden, Menelaos Pangalos, Barrett Nuttall, Pinar Akcakaya, Grzegorz Sienski, Marcello Maresca

Journal: Nat Commun

PubMed ID: 37673883

Doi: 10.1038/s41467-023-41240-7

Products & Services: Proteins, Expression, Isolation and Analysis

Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II

Authors: David Flores-Solis, Irina P Lushpinskaia, Anton A Polyansky, Arya Changiarath, Marc Boehning, Milana Mirkovic, James Walshe, Lisa M Pietrek, Patrick Cramer, Lukas S Stelzl, Bojan Zagrovic, Markus Zweckstetter

Journal: Nat Commun

PubMed ID: 37749095

Doi: 10.1038/s41467-023-41633-8

Products & Services: Proteins, Expression, Isolation and Analysis

One-step production of fully biotinylated and glycosylated human Fc gamma receptors

Authors: Minhyo Kang, Zening Wang, Xin Ge

Journal: Biotechnol Prog

PubMed ID: 37734055

Doi: 10.1002/btpr.3392

Products & Services: Proteins, Expression, Isolation and Analysis

Oligomeric State of β-Coronavirus Non-Structural Protein 10 Stimulators Studied by Small Angle X-ray Scattering

Authors: Wolfgang Knecht, S Zoë Fisher, Jiaqi Lou, Céleste Sele, Shumeng Ma, Anna Andersson Rasmussen, Nikos Pinotsis, Frank Kozielski