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Rational Design of Taxadiene Hydroxylase by Ancestral Enzyme Construction and the Elucidation of Key Amino Acids
Authors: Zihan Zhang, Longhao Huang, Zhi-Jun Zhang, Jian-He Xu, Hui-Lei Yu
Journal: Biochemistry
PubMed ID: 37902563
Doi: 10.1021/acs.biochem.3c00411
FHL1 promotes chikungunya and o'nyong-nyong virus infection and pathogenesis with implications for alphavirus vaccine design
Authors: Wern Hann Ng, Xiang Liu, Zheng L Ling, Camilla N O Santos, Lucas S Magalhães, Andrew J Kueh, Marco J Herold, Adam Taylor, Joseph R Freitas, Sandra Koit, Sainan Wang, Andrew R Lloyd, Mauro M Teixeira, Andres Merits, Roque P Almeida, Nicholas J C King, Suresh Mahalingam
Journal: Nat Commun
PubMed ID: 37884534
Doi: 10.1038/s41467-023-42330-2
Biochemical and biophysical properties of a rare TTRA81V mutation causing mild transthyretin amyloid cardiomyopathy
Authors: Qiuyan Sha, Yanli Zhang, Mengdie Wang, Jialu Sun, Yunlong Zhang, Xinxin Zhang, Ning Wang, Yu Liu, Ying Liu
Journal: ESC Heart Fail
PubMed ID: 37827496
Doi: 10.1002/ehf2.14543
ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1
Authors: Karin Enell Smith, Sara Fritzell, Anneli Nilsson, Karin Barchan, Anna Rosén, Lena Schultz, Laura Varas, Anna Säll, Nadia Rose, Maria Håkansson, Laura von Schantz, Peter Ellmark
Journal: Cancer Immunol Immunother
PubMed ID: 37796298
Doi: 10.1007/s00262-023-03548-7
Products & Services: Gene Synthesis   
Industry updates from the field of stem cell research and regenerative medicine in August 2023
Authors: Dusko Ilic, Mirjana Liovic
Journal: Regen Med
PubMed ID: 37786963
Doi: 10.2217/rme-2023-0181
Author Correction: A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates
Authors: Payton A-B Weidenbacher, Mrinmoy Sanyal, Natalia Friedland, Shaogeng Tang, Prabhu S Arunachalam, Mengyun Hu, Ozan S Kumru, Mary Kate Morris, Jane Fontenot, Lisa Shirreff, Jonathan Do, Ya-Chen Cheng, Gayathri Vasudevan, Mark B Feinberg, Francois J Villinger, Carl Hanson, Sangeeta B Joshi, David B Volkin, Bali Pulendran, Peter S Kim
Journal: Nat Commun
PubMed ID: 37798288
Doi: 10.1038/s41467-023-42061-4
Products & Services: Peptide Synthesis   
LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway
Authors: Kai-Jie He, Jin-Bao Zhang, Jun-Yi Liu, Feng-Lun Zhao, Xiao-Yu Yao, Yu-Ting Tang, Jin-Ru Zhang, Xiao-Yu Cheng, Li-Fang Hu, Fen Wang, Chun-Feng Liu
Journal: iScience
PubMed ID: 37876795
Doi: 10.1016/j.isci.2023.108130
Products & Services: Molecular Biology Reagents   
Development and characterization of a prototypic pan-amyloid clearing agent - a novel murine peptide-immunoglobulin fusion
Authors: James S Foster, Manasi Balachandran, Trevor J Hancock, Emily B Martin, Sallie Macy, Craig Wooliver, Tina Richey, Alan Stuckey, Angela D Williams, Joseph W Jackson, Stephen J Kennel, Jonathan S Wall
Journal: Front Immunol
PubMed ID: 37854603
Doi: 10.3389/fimmu.2023.1275372
Products & Services: Molecular Biology Reagents   
Dendritic Cell-Mediated Cross-Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS-CoV-2
Authors: Rodrigo Lázaro-Gorines, Patricia Pérez, Ignacio Heras-Murillo, Irene Adán-Barrientos, Guillermo Albericio, David Astorgano, Sara Flores, Joanna Luczkowiak, Nuria Labiod, Seandean L Harwood, Alejandro Segura-Tudela, Laura Rubio-Pérez, Yudhi Nugraha, Xiaoran Shang, Yuxing Li, Carlos Alfonso, Kaylin A Adipietro, Dinendra L Abeyawardhane, Rocío Navarro, Marta Compte, Wenbo Yu, Alexander D MacKerell, Laura Sanz, David J Weber, Francisco J Blanco, Mariano Esteban, Edwin Pozharski, Raquel Godoy-Ruiz, Inés G Muñoz, Rafael Delgado, David Sancho, Juan García-Arriaza, Luis Álvarez-Vallina
Journal: Adv Sci (Weinh)
PubMed ID: 37863812
Doi: 10.1002/advs.202304818
Examining the Potential Formation of Ternary DNA Complexes with Chromium‑Cysteine, Chromium-Ascorbate, and Chromium-Glutathione and Implications for Their Carcinogenicity
Authors: Sydney Marchi , Emma Lankford , Bradley Dorin , Eilidh Drummond , Sumner C Thomas , Stephen A Woski , John B Vincent
Journal: Biol Trace Elem Res .
PubMed ID: 36662348
Doi: 10.1007/s12011-023-03573-8
Products & Services: Custom DNA/RNA Oligos   

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