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A model of human neural networks reveals NPTX2 pathology in ALS and FTLD

Authors: Marian Hruska-Plochan, Vera I Wiersma, Katharina M Betz, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma , Laura De Vos, Karl Frontzek , Adriano Aguzzi, Tammaryn Lashley , Mark D Robinson, Theofanis Karayannis, Martin Mueller, Andreas Hierlemann 4, Magdalini Polymenidou 13

Journal: Nature

PubMed ID: 38355792

Doi: 10.1038/s41586-024-07042-7

Products & Services: Gene Synthesis

Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel Na18 with a Unique Mechanism of Action

Authors: John M Gilchrist, Nien-Du Yang, Victoria Jiang, Bryan D Moyer

Journal: Mol Pharmacol

PubMed ID: 38195157

Doi: 10.1124/molpharm.123.000789

Products & Services: Mutagenesis Services

The ETI-dependent receptor-like kinase 1 positively regulates effector-triggered immunity by stabilizing NLR-required for cell death 4 in Nicotiana benthamiana

Authors: Yujing Sun, Fan Liu, Mengzhu Zeng, Xinjie Zhang, Ying Cui, Zhaodan Chen, Lei Wang, Yuanpeng Xu, Jinbin Wu, Shengya Guo, Xian Dong, Suomeng Dong, Yan Wang, Yuanchao Wang

Journal: New Phytol

PubMed ID: 38362937

Doi: 10.1111/nph.19596

Products & Services: DNA Sequencing

DNA polymerase iota promotes EMT and metastasis of esophageal squamous cell carcinoma by interacting with USP7 to stabilize HIF-1α

Authors: Aidi Gao, Mingxia Zhang, Shuang Qi Zhu, Shitao Zou, Hengrui Chen, Xiaoqin Li, Chao He, Liangsu Zhou, Yan Mei, Weiqun Ding, Jundong Zhou, Yue Zhou, Yuandong Cao

Journal: Cell Death Dis

PubMed ID: 38402183

Doi: 10.1038/s41419-024-06552-6

Products & Services: Proteins, Expression, Isolation and Analysis

SARS-CoV-2 Membrane protein regulates the function of Spike by inhibiting its plasma membrane localization and enzymatic activity of Furin

Authors: Qi Xiang, Jie Wu, Yuzheng Zhou, Linhao Li, Miao Tian, Guobao Li, Zheng Zhang, Yang Fu

Journal: Microbiol Res

PubMed ID: 38430890

Doi: 10.1016/j.micres.2024.127659

Products & Services: Serology SARS-Cov-2 detection kits

Proteomic analysis of milk fat globule membrane proteins in mature human milk of women with and without gestational diabetes mellitus

Authors: Dan Yao, Cai Shen, Jingwen Yu, Jiayue Tang, Hong Zhang, Xuebing Xu, Maolin Tu, Ling-Zhi Cheong