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Integrative functional genomics decodes herpes simplex virus 1

Authors: Adam W Whisnant, Christopher S Jürges, Thomas Hennig, Emanuel Wyler, Bhupesh Prusty, Andrzej J Rutkowski, Anne L'hernault, Lara Djakovic, Margarete Göbel, Kristina Döring, Jennifer Menegatti, Robin Antrobus, Nicholas J Matheson, Florian W H Künzig, Guido Mastrobuoni, Chris Bielow, Stefan Kempa, Chunguang Liang, Thomas Dandekar, Ralf Zimmer, Markus Landthaler, Friedrich Grässer, Paul J Lehner, Caroline C Friedel, Florian Erhard, Lars Dölken

Journal: Nat Commun

PubMed ID: 32341360

Doi: 10.1038/s41467-020-15992-5

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ACSL4 promotes hepatocellular carcinoma progression via c-Myc stability mediated by ERK/FBW7/c-Myc axis

Authors: Chen J, Ding C, Chen Y, Hu W, Lu Y, Wu W, Zhang Y, Yang B, Wu H, Peng C, Xie H, Zhou L, Wu J, Zheng S

Journal: Oncogenesis

PubMed ID: 32350243

Doi: 10.1038/s41389-020-0226-z

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Germline Mutations in FAF1 Are Associated With Hereditary Colorectal Cancer

Authors: Laia Bonjoch, Sebastià Franch-Expósito, Pilar Garre, Sami Belhadj, Jenifer Muñoz, Coral Arnau-Collell, Marcos Díaz-Gay, Anna Gratacós-Mulleras, Giulia Raimondi, Clara Esteban-Jurado, Yasmin Soares de Lima, Cristina Herrera-Pariente, Miriam Cuatrecasas, Teresa Ocaña, Antoni Castells, Cristina Fillat, Gabriel Capellá, Francesc Balaguer, Trinidad Caldés, Laura Valle, Sergi Castellví-Bel

Journal: Gastroenterology

PubMed ID: 32179092

Doi: 10.1053/j.gastro.2020.03.015

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Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

Authors: Saskia Hoffmann, Satyakrishna Pentakota, Andreas Mund, Peter Haahr, Fabian Coscia, Marta Gallo, Matthias Mann, Nicholas M. I. Taylor, Niels Mailand

Journal: biorxiv

Doi: 10.1101/2020.03.16.993600

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The KSHV ORF34 protein Interacts and Stabilizes HIF-2α via Binding to the HIF-2α bHLH and PAS Domains.

Authors: HaqueMuzammel，Kousoula

Journal: J. Virol.

PubMed ID: 31189709

Doi: 10.1128/JVI.00764-19

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Interaction and Regulation Between Lipid Mediator Phosphatidic Acid and Circadian Clock Regulators.

Authors: KimSang-Chul，NusinowDmitri A，SorkinMaria L，Pruneda-PazJose，WangXu

Journal: Plant Cell

PubMed ID: 30674693

Doi: 10.1105/tpc.18.00675

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Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1

Authors: Zhang J1, Ali AM2, Lieu YK3, Liu Z4, Gao J1, Rabadan R4, Raza A5, Mukherjee S6, Manley JL7.

Journal: Mol Cell.

PubMed ID: 31474574

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The Bromodomain Protein 4 Contributes to the Regulation of Alternative Splicing

Authors: Uppal S, Gegonne A, Chen Q, Thompson PS, Cheng D, Mu J, Meerzaman D, Misra HS, Singer DS

Journal: Cell Rep

PubMed ID: 31747612

Doi: 10.1016/j.celrep.2019.10.066

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PARP1 Suppresses the Transcription of PD-L1 by Poly(ADP-Ribosyl)ating STAT3.

Authors: DingLing，ChenXi，XuXiaqing，QianYuli，LiangGuikai，YaoFengqi，YaoZhangting，WuHonghai，ZhangJieqiong，HeQiaojun，Ya

Journal: Cancer Immunol Res

PubMed ID: 30401677

Doi: 10.1158/2326-6066.CIR-18-0071

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Identification of NMS-873， an allosteric and specific p97 inhibitor， as a broad antiviral against both influenza A and B viruses.

Authors: ZhangJiantao，HuYanmei，HauRaymond，MusharrafiehRami，MaChunlong，ZhouXu，ChenYin，Wan

Journal: Eur J Pharm Sci

PubMed ID: 30930289

Doi: 10.1016/j.ejps.2019.03.020

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