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Mycobacterium abscessus VapC5 toxin potentiates evasion of antibiotic killing by ribosome overproduction and activation of multiple resistance pathways
Authors: Eduardo A Troian, Heather M Maldonado, Unnati Chauhan, Valdir C Barth, Nancy A Woychik
Journal: Nat Commun
PubMed ID: 37349306
Doi: 10.1038/s41467-023-38844-4
Products & Services: Combinatorial DNA Libraries   
Knockdown of Yap attenuates TAA-induced hepatic fibrosis by interaction with hedgehog signals
Authors: Ye Zhao, Huiling Wang, Tianhua He, Bo Ma, Guoguang Chen, Chimeng Tzeng
Journal: J Cell Commun Signal
PubMed ID: 37338798
Doi: 10.1007/s12079-023-00775-6
Products & Services: Gene Synthesis   
Identification and Characterization of an HtrA Sheddase Produced by Coxiella burnetii
Authors: Ikram Omar Osman , Aurelia Caputo , Lucile Pinault , Jean-Louis Mege , Anthony Levasseur , Christian A Devaux
Journal: Int J Mol Sci .
PubMed ID: 37446087
Doi: 10.3390/ijms241310904
Products & Services: Gene Synthesis   
Spatiotemporal and global profiling of DNA–protein interactions enables discovery of low-affinity transcription factors
Authors: An-Di Guo , Ke-Nian Yan, Hao Hu , Linhui Zhai , Teng-Fei Hu , Haixia Su , Yijia Chi , Jinyin Zha , Yechun Xu , Dongxin Zhao , Xiaojie Lu , Yong-Jiang Xu , Jian Zhang , Minjia Tan, Xiao-Hua Chen
Journal: Nat Chem .
PubMed ID: 37106095
Doi: 10.1038/s41557-023-01196-z
Products & Services: Peptide Synthesis   
Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing
Authors: Hyatt Balke-Want, Vimal Keerthi, Nikolaos Gkitsas, Andrew G Mancini, Gavin L Kurgan, Carley Fowler, Peng Xu, Xikun Liu, Kyle Asano, Sunny Patel, Christopher J Fisher, Annie K Brown, Ramya H Tunuguntla, Shabnum Patel, Elena Sotillo, Crystal L Mackall, Steven A Feldman
Journal: Mol Cancer
PubMed ID: 37365642
Doi: 10.1186/s12943-023-01799-7
Products & Services: Proteins, Expression, Isolation and Analysis   
Genome-wide characterization of extrachromosomal circular DNA in gastric cancer and its potential role in carcinogenesis and cancer progression
Authors: Xianming Jiang, Xiaoguang Pan, Wenchao Li, Peng Han, Jiaying Yu, Jing Li, Haoran Zhang, Wei Lv, Ying Zhang, Yulong He, Xi Xiang
Journal: Cell Mol Life Sci
PubMed ID: 37369919
Doi: 10.1007/s00018-023-04838-0
Products & Services: Proteins, Expression, Isolation and Analysis   
CLDN182 and 4-1BB bispecific antibody givastomig exerts antitumor activity through CLDN182-expressing tumor-directed T-cell activation
Authors: Jing Gao, Zhengyi Wang, Wenqing Jiang, Yanni Zhang, Zhen Meng, Yanling Niu, Zhen Sheng, Chan Chen, Xuejun Liu, Xi Chen, Chanjuan Liu, Keren Jia, Cheng Zhang, Haiyan Liao, Jaeho Jung, Eunsil Sung, Hyejin Chung, Jingwu Z Zhang, Andrew X Zhu, Lin Shen
Journal: J Immunother Cancer
PubMed ID: 37364935
Doi: 10.1136/jitc-2023-006704
Products & Services: Proteins, Expression, Isolation and Analysis   
ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway
Authors: Songnan Wang, Volker Böhnert, Alby J Joseph, Valentino Sudaryo, Jason Swinderman, Feiqiao B Yu, Xuchao Lyu, Gemini Skariah, Vishvak Subramanyam, Luke A Gilbert, Hani Goodarzi, Li Lingyin
Journal: biorxiv
PubMed ID: 37333273
Doi: 10.1101/2023.06.01.543353
Products & Services: Proteins, Expression, Isolation and Analysis   
Durable contraception in the female domestic cat using viral-vectored delivery of a feline anti-Müllerian hormone transgene
Authors: Lindsey M Vansandt, Marie-Charlotte Meinsohn, Philippe Godin, Nicholas Nagykery, Natalie Sicher, Motohiro Kano, Aki Kashiwagi, Maeva Chauvin, Hatice D Saatcioglu, Julie L Barnes, Amy G Miller, Amy K Thompson, Helen L Bateman, Elizabeth M Donelan, Raquel González, Jackie Newsom, Guangping Gao, Patricia K Donahoe, Dan Wang, William F Swanson, David Pépin
Journal: Nat Commun
PubMed ID: 37280258
Doi: 10.1038/s41467-023-38721-0
Products & Services: Codon Optimization   
Novel SPEA Superantigen Peptide Agonists and Peptide Agonist-TGFαL3 Conjugate In Vitro Study of Their Growth-Inhibitory Effects for Targeted Cancer Immunotherapy
Authors: Sara S Bashraheel, Sayed K Goda
Journal: Int J Mol Sci
PubMed ID: 37445686
Doi: 10.3390/ijms241310507
Products & Services: Peptide Synthesis   

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