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Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
Authors: Tong Han, Xujun Wang, Sailing Shi, Wubing Zhang, Jue Wang, Qiu Wu, Ziyi Li, Jingxin Fu, Rongbin Zheng, Jiamin Zhang, Qin Tang, Peng Zhang, Chenfei Wang
Journal: cancer immunology research
PubMed ID: 36629846
Doi: 10.1158/2326-6066.CIR-22-0056
HJM-561, a Potent, Selective, and Orally Bioavailable EGFR PROTAC that Overcomes Osimertinib-Resistant EGFR Triple Mutations
Authors: Yong Du, Yongfeng Chen, Yuxia Wang, Jinju Chen, Xiaorong Lu, Li Zhang, Yan Li, Zhaofu Wang, Guozhong Ye, George Zhang
Journal: Mol Cancer Ther
PubMed ID: 35499406
Doi: 10.1158/1535-7163.MCT-21-0835
A prion-like domain of TFEB mediates the co-aggregation of TFEB and mHTT
Authors: Junsheng Yang, Huilin Xu, Chaoyue Zhang, Xiaotong Yang, Weijie Cai, Xiaoli Chen
Journal: Autophagy
PubMed ID: 35635192
Doi: 10.1080/15548627.2022.2083857
A plant immune protein enables broad antitumor response by rescuing microRNA deficiency
Authors: Ye Qi , Li Ding , Siwen Zhang , Shengze Yao , Jennie Ong , Yi Li , Hong Wu , Peng Du
Journal: Cell
PubMed ID: 35623329
Doi: 10.1016/j.cell.2022.04.030
Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance
Authors: Yalan Deng, Xianghou Xia, Yang Zhao, Zilong Zhao, Consuelo Martinez, Wenjuan Yin, Jun Yao, Qinglei Hang, Weiche Wu, Jie Zhang, Yang Yu, Weiya Xia, Fan Yao, Di Zhao, Yutong Sun, Haoqiang Ying, Mien-Chie Hung, Li Ma
Journal: Nat Commun
PubMed ID: 34873175
Doi: 10.1038/s41467-021-27349-7
Mechanisms underlying astrocytic connexin-43 autophagy degradation during cerebral ischemia injury and the effect on neuroinflammation and cell apoptosis
Authors: Wang X, Feng L, Xin M, Hao Y, Wang X, Shang P, Zhao M, Hou S, Zhang Y, Xiao Y, Ma D, Feng J
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
PubMed ID: 32361163
Doi: 10.1016/j.biopha.2020.110125
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