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A study of the value of requesting information from drug manufacturers for systematic reviews; 9 years of experience from the drug effectiveness review project.

Syst Rev. 2018-10; 
McDonaghMarian S,ThakurtaSujata,Peterso
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ORF cDNA Clones/MolecularCloud … Molecular cloning The secreted portions of wild type and K12del canine RBP4 cDNAs (accession XM_534969, GenScript, Piscataway, NJ, USA) were subcloned into pUS2 vector, downstream of the human RBP4 signal peptide (MKWVWALLLLAALGSGRA) and HA epitope tag … Get A Quote

摘要

Systematic reviews (SRs) depend on comprehensive searches for evidence to provide balanced, accurate results. Requesting published and unpublished studies from pharmaceutical manufacturers has been proposed as a method to engage industry stakeholders and potentially reduce reporting bias. The Drug Effectiveness Review Project (DERP) has been requesting such evidence since 2003; the purpose of this study was to retrospectively evaluate the type and impact of the evidence received.

关键词

Gray literature,Pharmaceutical manufacturers,Publication bias,Reporting bias,Systematic rev