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Gene Synthesis> | … bls tag (CellFree Sciences, Matsuyama, Japan). P. vivax genes were obtained either from parent clones [22], using SAL-1 cDNA, or commercially synthesized from Genscript (Japan). DNA template for WGCF was prepared from … | Get A Quote |
Plasmodium vivax remains an important cause of malaria in South America and the Asia-Pacific. Naturally acquired antibody responses against multiple P. vivax proteins have been described in numerous countries, however, direct comparison of these responses has been difficult with different methodologies employed. We measured antibody responses against 307 P. vivax proteins at the time of P. vivax infection, and at 2-3 later time-points in three countries. We observed that seropositivity rates at the time of infection were highest in Thailand, followed by Brazil then PNG, reflecting the level of antigenic input. The majority of sero-reactive antigens in all sites induced short-lived antibody responses w... More