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Proteins, Expression, Isolation and Analysis> | … 2.7. Apoptosis Detection. The paraffin-embedded liver sections were assayed using the terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) Apoptosis Kit (GenScript, Piscataway, NJ, USA) according to the manufacturer's protocol [21]. 2.8 … | Get A Quote |
Malaria is a dangerous disease spread across several countries. Recent studies have focused on medicinal plants to discover alternative agents to the currently used drugs for malaria treatment. Here, we investigated the potential role of leaf extract (IE) on hepatic inflammation in mice with -infected erythrocytes. Female C57BL/6 mice were divided into three groups. The first group served as a control noninfected group, while the second and third groups were intraperitoneally injected with 10 erythrocytes parasitized by . Mice from the third group were treated daily with a dose of 100 mg/kg of IE for 7 days. IE significantly reduced the number of leukocytes and apoptotic cells. The numbers of CD68-positi... More