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Development and Validation of Apolipoprotein AI-Associated Lipoprotein Proteome Panel for the Prediction of Cholesterol Efflux Capacity and Coronary Artery Disease.

Clin. Chem.. 2019; 
JinZhicheng,CollierTimothy S,DaiDarlene L Y,ChenVirginia,HollanderZsuzsanna,NgRaymond T,McManusBruce M,BalshawRobert,ApostolidouSophia,PennMarc S,Bystrom
Products/Services Used Details Operation
Biochemicals His6-tagged and 16Nlabeled apo AI was purchased from Genscript Get A Quote

摘要

Cholesterol efflux capacity (CEC) is a measure of HDL function that, in cell-based studies, has demonstrated an inverse association with cardiovascular disease. The cell-based measure of CEC is complex and low-throughput. We hypothesized that assessment of the lipoprotein proteome would allow for precise, high-throughput CEC prediction.

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