Peroxiredoxins (Prxs) are a novel group of peroxidases containing high antioxidant efficiency. The mammalian Prx family has six distinct members (Prx I-VI) in various subcellular locations， including peroxisomes and mitochondria， places where oxidative stress is most evident. The function of Prx I in particular has been implicated in regulating cell proliferation， differentiation， and apoptosis. Since thioredoxin1 (Trx1) as an electron donor is functionally associated with Prx I， we investigated levels of expression of both Prx I and Trx1.
Peroxiredoxins (Prxs) are a novel group of peroxidases containing high antioxidant efficiency. The mammalian Prx family has six distinct members (Prx I-VI) in various subcellular locations， including peroxisomes and mitochondria， places where oxidative stress is most evident. The function of Prx I in particular has been implicated in regulating cell proliferation， differentiation， and apoptosis. Since thioredoxin1 (Trx1) as an electron donor is functionally associated with Prx I， we investigated levels of expression of both Prx I and Trx1.
