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Hypermucoviscous Klebsiella pneumoniae infections induce platelet aggregation and apoptosis and inhibit maturation of megakaryocytes.

Thromb. Res.. 2018; 
WangZhiwei,RenJianan,LiuQinjie,LiJiayang,WuXiuwen,WangWeiping,WuJie,WangGefei,LiJie
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Proteins, Expression, Isolation and Analysis … 2.11. LPS measurement. The concentration of LPS was measured by the chromogenic end-point Tachypleus amebocyte lysate (CE TAL) assay kit (GenScript, USA) from 1:25 diluted PRP samples. This experiment was performed in triplicate … Get A Quote

摘要

Different Klebsiella pneumoniae strains carry different virulence factors and antibiotic resistance and may cause thrombocytopenia. This study aimed to investigate the effects of different infections caused by K. pneumoniae on platelets.

关键词

Aggregation,Apoptosis,Carbapenem resistance,Hypermucoviscous,Klebsiella pneumoniae,Megakaryocytopoiesis,Platelets,Thrombocytop