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Macrophage migration inhibitory factor promotes resistance to MEK blockade in KRAS mutant colorectal cancer cells.

Mol Oncol. 2018; 
CheonSeul-Ki,KimHwang-Phill,ParkYe-Lim,JangJee-Eun,LimYoojoo,SongSang-Hyun,HanSae-Won,KimTae
Products/Services Used Details Operation
Gene Synthesis The amplified fragments were cloned into the pCMV‐Tag2B simple vector (Addgene, Cambridge, MA, USA). sgRNA targeting MIF were designed using the genscript online tool (http://www.genscript.com). Get A Quote

摘要

Department of Molecular Medicine & Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Korea.,Department of Molecular Medicine & Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Korea.,Department of Molecular Medicine & Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Korea.,Cancer Research Institute, Seoul National University, Korea.,Department of Internal Medicine, Seoul National University Hospital, Korea.,Cancer Research Institute, Seoul National University, Korea.,Cancer Research Institut... More

关键词

KRAS,MIF,colorectal cancer,feedback mechanism,refamet