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Quercetin Improves Inflammation, Oxidative Stress, and Impaired Wound Healing in Atopic Dermatitis Model of Human Keratinocytes

Pediatric Allergy. 2020-06;

Burcin Beken, Riza Serttas, Mehtap Yazicioglu, Kader Turkekul, and Suat Erdogan

Products/Services Used	Details	Operation
Recombinant Proteins	… Cells were incubated at 37°C and 5% CO 2. Quercetin, dexamethasone (Sigma-Aldrich Chemie, Taufkirchen, Germany), IL-4 (Thermo Fisher Scientific, Waltham, MA), IL-13 , and TNF-α (GenScript, Piscataway) were dissolved in dimethyl sulfoxide (DMSO …	Get A Quote

摘要

Atopic dermatitis (AD) is a common inflammatory skin disease with complex pathogenesis. Natural flavonoids exhibit strong anti-inflammatory and antioxidant properties in many human diseases. In this study, the potential bioactive effect of quercetin, a polyphenolic plant-derived flavonoid, on the AD model of human keratinocytes was evaluated.