| Products/Services Used | Details | Operation |
|---|---|---|
| Peptide Synthesis | … Synthetic peptides were ordered from GenScript (China, Beijing) and used for development of antibodies and … Biological relevance of the biomarker was screened in patient samples from a HFpEF … reader at 450 nm with 650 nm as the reference (Molecular Devices, SpectraMax … | Get A Quote |
Increased turnover of extracellular matrix proteins is seen in many different diseases and is an underlying and driving feature of pathogenesis. An increased ratio of formation over degradation of extracellular matrix proteins, such as collagens, leads to accumulation of proteins in the tissues, ultimately impairing organ function. Understanding how this balance is regulated is key to providing deeper insight into high extracellular matrix turnover diseases. Type XXVIII collagen is a novel collagen with limited information available in relation to expression, tissue prevalence and clinical implication. We generated a novel, technically robust ELISA to measure a C-terminal fragment of type XXVIII collagen in pla... More
