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A dry powder formulation for peripheral lung delivery and absorption of an anti-SARS-CoV-2 ACE2 decoy polypeptide

Authors: Stefania Glieca, Davide Cavazzini, Elisabetta Levati, Valentina Garrapa, Angelo Bolchi, Valentina Franceschi, Simone Odau, Simone Ottonello, Gaetano Donofrio, Jonas Füner, Fabio Sonvico, Ruggero Bettini, Barbara Montanini, Francesca Buttini

Journal: Eur J Pharm Sci

PubMed ID: 37838239

Doi: 10.1016/j.ejps.2023.106609

Products & Services: Proteins, Expression, Isolation and Analysis

Creating Designer Engineered Extracellular Vesicles for Diverse Ligand Display, Target Recognition, and Controlled Protein Loading and Delivery

Authors: Alena Ivanova, Lukas Badertscher, Gwen O'Driscoll, Joakim Bergman, Euan Gordon, Anders Gunnarsson, Camilla Johansson, Michael J Munson, Cristiana Spinelli, Sara Torstensson, Liisa Vilén, Andrei Voirel, John Wiseman, Janusz Rak, Niek Dekker, Elisa Lázaro-Ibáñez

Journal: Adv Sci (Weinh)

PubMed ID: 37867228

Doi: 10.1002/advs.202304389

Products & Services: Proteins, Expression, Isolation and Analysis

Hypoxia-responsive CAR-T cells exhibit reduced exhaustion and enhanced efficacy in solid tumors

Authors: Xiuxiu Zhu, Jun Chen, Wuling Li, Yanmin Xu, Juanjuan Shan, Juan Hong, Yongchun Zhao, Huailong Xu, Jiabing Ma, Junjie Shen, Cheng Qian

Journal: Cancer Res

PubMed ID: 37874330

Doi: 10.1158/0008-5472.CAN-23-1038

Products & Services: Proteins, Expression, Isolation and Analysis

X-ray crystallography study and optimization of novel benzothiophene analogs as potent selective estrogen receptor covalent antagonists (SERCAs) with improved potency and safety profiles

Authors: Chengfeng Bai, Yang Lv, Shuangshuang Xiong, Shuangjie Wu, Lin Qi, Shengnan Ren, Meiqi Zhu, Haijuan Dong, Hongtao Shen, Zhaoxing Li, Yinxue Zhu, Hui Ye, Haiping Hao, Yibei Xiao, Hua Xiang, Guoshun Luo

Journal: Bioorg Chem

PubMed ID: 37871388

Doi: 10.1016/j.bioorg.2023.106919

Products & Services: Proteins, Expression, Isolation and Analysis

CTNNBIP1-CLSTN1 functions as a housekeeping chimeric RNA and regulates cell proliferation through SERPINE2

Authors: Chen Chen, Fujun Qin, Sandeep Singh, Yue Tang, Hui Li

Journal: Cell Death Discov

PubMed ID: 37805599

Doi: 10.1038/s41420-023-01668-8

Products & Services: Proteins, Expression, Isolation and Analysis

becomes lethal to post-larvae shrimp via acquiring novel virulence factors

Authors: Shuang Liu, Wei Wang, Tianchang Jia, Lusheng Xin, Ting-Ting Xu, Chong Wang, Guosi Xie, Kun Luo, Jun Li, Jie Kong, Qingli Zhang

Journal: Microbiol Spectr

PubMed ID: 37850796

Doi: 10.1128/spectrum.00492-23

Products & Services: Proteins, Expression, Isolation and Analysis

Ablation of the GDP-fucose transporter suppresses lung cancer cell proliferation and migration by reducing expression of PD-L1

Authors: Yingshu Zhang, Nianzhu Zhang, Wanli Song, Sabiha Yousuf, Wenzhe Li

Journal: J Cancer

PubMed ID: 37928424

Doi: 10.7150/jca.84652

Products & Services: Proteins, Expression, Isolation and Analysis

Enhanced protective efficacy of a thermostable RBD-S2 vaccine formulation against SARS-CoV-2 and its variants

Authors: Nidhi Mittal, Sahil Kumar, Raju S Rajmani, Randhir Singh, Céline Lemoine, Virginie Jakob, Sowrabha Bj, Nayana Jagannath, Madhuraj Bhat, Debajyoti Chakraborty, Suman Pandey, Aurélie Jory, Suba Soundarya Sa, Harry Kleanthous, Patrice Dubois, Rajesh P Ringe, Raghavan Varadarajan

Journal: npj Vaccines

PubMed ID: 37880298

Doi: 10.1038/s41541-023-00755-2

Products & Services: Proteins, Expression, Isolation and Analysis

Recovery of protein synthesis to assay DNA repair activity in transcribed genes in living cells and tissues

Authors: Melanie van der Woude, Carlota Davó-Martínez, Karen L Thijssen, Wim Vermeulen, Hannes Lans

Journal: Nucleic Acids Res

PubMed ID: 37522336

Doi: 10.1093/nar/gkad642

Products & Services: Proteins, Expression, Isolation and Analysis

Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease

Authors: Xingyu Zhang, Li Tang, Jiaolong Yang, Lanxia Meng, Jiehui Chen, Lingyan Zhou, Jiangyu Wang, Min Xiong, Zhentao Zhang