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Regulation of N-degron recognin-mediated autophagy by the SARS-CoV-2 PLpro ubiquitin deconjugase

Authors: Carlos Ayala-Torres , Jiangnan Liu , Nico P Dantuma , Maria G Masucci

Journal: Autophagy

PubMed ID: 39723606

Doi: 10.1080/15548627.2024.2442849

Products & Services: Gene Synthesis

Reconstitution of human DNA licensing and the structural and functional analysis of key intermediates

Authors: Jennifer N. Wells, Lucy V. Edwardes, Vera Leber, Shenaz Allyjaun, Matthew Peach, Joshua Tomkins, Antonia Kefala-Stavridi, Sarah V. Faull, Ricardo Aramayo, Carolina M. Pestana, Lepakshi Ranjha & Christian Speck

Journal: Nature Communications

PubMed ID: 39779677

Doi: 10.1038/s41467-024-55772-z

Products & Services: Gene Synthesis

Screening the human miRNA interactome reveals coordinated up-regulation in melanoma, adding bidirectional regulation to miRNA networks

Authors: Faezeh Jame-Chenarboo , Joseph N Reyes , Nicholas M Twells , Hoi Hei Ng , Dawn Macdonald , Eva Hernando , Lara K Mahal

Journal: SCIENCE ADVANCES

PubMed ID: 39792681

Doi: 10.1126/sciadv.adr0277

Products & Services: Gene Synthesis

Dietary amino acids promote glucagon-like hormone release to generate global calcium waves in adipose tissues in Drosophila

Authors: Muhammad Ahmad, Shang Wu, Shengyao Luo, Wenjia Shi, Xuan Guo, Yuansheng Cao, Norbert Perrimon & Li He

Journal: Nature Communications

PubMed ID: 39747032

Doi: 10.1038/s41467-024-55371-y

Products & Services: Peptide Synthesis

MCM2-7 ring closure involves the Mcm5 C-terminus and triggers Mcm4 ATP hydrolysis

Authors: Sarah V. Faull, Marta Barbon, Audrey Mossler, Zuanning Yuan, Lin Bai, L. Maximilian Reuter, Alberto Riera, Christian Winkler, Indiana Magdalou, Matthew Peach, Huilin Li & Christian Speck

Journal: Nature Communications

PubMed ID: 39747125

Doi: 10.1038/s41467-024-55479-1

Products & Services: Mutagenesis Services

Probing SARS-CoV-2 membrane binding peptide via single-molecule AFM-based force spectroscopy

Authors: Qingrong Zhang, Raissa S. L. Rosa, Ankita Ray, Kimberley Durlet, Gol Mohammad Dorrazehi, Rafael C. Bernardi & David Alsteens

Journal: Nature Communications

PubMed ID: 39747000

Doi: 10.1038/s41467-024-55358-9

Products & Services: Peptide Synthesis

Mismatch prime editing gRNA increased efficiency and reduced indels

Authors: Jidong Fei , Dongdong Zhao , Caiyi Pang , Ju Li , Siwei Li , Wentao Qiao , Juan Tan , Changhao Bi , Xueli Zhang

Journal: Nat Commun

PubMed ID: 39747083

Doi: 10.1038/s41467-024-55578-z

Products & Services: Synthetic Guide RNA

Systematic functional characterization of non-coding regulatory SNPs associated with central obesity

Authors: Shan-Shan Dong, Yuan-Yuan Duan, Ren-Jie Zhu, Ying-Ying Jia, Jia-Xin Chen, Xiao-Ting Huang, Shi-Hao Tang, Ke Yu, Wei Shi, Xiao-Feng Chen, Feng Jiang, Ruo-Han Hao, Yunlong Liu, Zhongbo Liu, Yan Guo, and Tie-Lin Yang

Journal: The American Journal of Human Genetics

Doi: doi.org/10.1016/j.ajhg.2024.11.005

Products & Services: Custom DNA/RNA Oligos Oligo pool

Salivary elicitor disulffde isomerase from Nilaparvata lugens targets host rice UDP-glucose epimerase 2 to induce plant defenses

Authors: Jianmei Fu , Zhichang Zhao , Jichao Fang , Rui Ji

Journal: Plant Stress

Doi: doi.org/10.1016/j.stress.2025.100744

Products & Services: Polyclonal Antibody Services

Energy-guided accumulated mutation strategy achieves a highly efficient polyethylene terephthalate-degrading enzyme

Authors: Zhi Wang, Jiaxing Zhang, Shengping You, Rongxin Su, Wei Qi

Journal: Biochemical Engineering Journal

Doi: 10.1016/j.bej.2025.109708

Products & Services: Protein and Antibody Isolation