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MechanismsofaureobasidinA inhibition and drug resistance in a fungal IPC synthase complex

Authors: Xinyue Wu , Xin Gong , Tian Xie

Journal: nature COMMUNICATION

PubMed ID: 40442105

Doi: doi.org/10.1038/s41467-025-60423-y

Products & Services: Protein and Antibody Isolation

DNA-Engineered Modular Nanovaccines Featuring Precise Topology for Enhanced Immunogenicity

Authors: Yanfei Qu, Dawei Wang, Yunlong Zhang, Fengyun Shen, Binghui Xia, Qin Xu, Qisheng Wang, Huating Kong, Ying Zhu, Lihua Wang, Itamar Willner, Xiurong Yang, Chunhai Fan, Lele Sun

Journal: ADVANCED MATERIALS

PubMed ID: 40371439

Doi: 10.1002/adma.202500577

Products & Services: Protein and Antibody Reagents

Deep Proteomic Profiling of the Intra-Golgi Trafficking Intermediates

Authors: Farhana Taher Sumya , Walter S Aragon-Ramirez , Vladimir V Lupashin

Journal: Molecular biology of the cell

PubMed ID: 40397568

Doi: 10.1091/mbc.E24-12-0556

Products & Services: Gene Synthesis

Programmatically activated DNA hydrogel microcapsules for precision therapy in inflammatory bowel disease

Authors: Peifen Lu, Hongxiu Yuan, Gang Wang, Yixi Dong, Runyu Zhao, Jia Man, Jianwei Jiao, Zhaoyin Wang, Jin Jiao

Journal: Theranostics

Doi: 10.7150/thno.111583

Products & Services: Protein and Antibody Isolation

Engineering galactose oxidase for biocatalytic synthesis of 2-(furan-2-yl)-2-oxoacetic acid, a critical precursor of cefuroxime

Authors: Tong Zhang, Hao Wei, Yunju Zhang, Tengteng Qi, Kehao Yuan, Bin Wang, Ziyan Zhang, Liangqing Chen, Qinyuan Ma, Xiuzhen Gao

Journal: Journal Pre-proof

Doi: 10.1016/j.gresc.2025.05.010

Cnidaria XIAP activates caspase-mediated cell death

Authors: Yuan Chen, Meng Wu, Zihao Yuan, Qingyue Wang, Hang Xu, Li Sun

Journal: International Journal of Biological Macromolecules

PubMed ID: 40288723

Doi: doi.org/10.1016/j.ijbiomac.2025.143427

Products & Services: Protein and Antibody Isolation

A fluorescence-based assay for measuring polyamine biosynthesis aminopropyl transferase mediated catalysis

Authors: Pallavi Singh; Jae-Yeon Choi; Weiwei Wang; Tukiet T. Lam; Philip Lechner; Christopher D. Vanderwal; Sovitj Pou; Aaron Nilsen; Choukri Ben Mamoun

Journal: The Journal of Biological Chemistry

PubMed ID: 39342998

Doi: 10.1016/j.jbc.2024.107832

Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors

Authors: Xujie Zhang; Lin Sun; Megan E. Meuser; Waleed A. Zalloum; Shujing Xu; Tianguang Huang; Srinivasulu Cherukupalli; Xiangyi Jiang; Xiao Ding; Yucen Tao; Dongwei Kang; Erik De Clercq; Christophe Pannecouque; Alexej Dick; Simon Cocklin; Xinyong Liu; Peng Zhan

Journal: European Journal of Medicinal Chemistry

PubMed ID: 34592608

Doi: 10.1016/j.ejmech.2021.113848

Products & Services: Peptide Synthesis

CAMPER: mechanistic artificial intelligence for designing peptides that target MRSA persisters

Authors: Fadi Shehadeh; Biswajit Mishra; Raquel Ferrer-Espada; Anindya Basu; LewisOscar Felix; Charilaos Dellis; Narchonai Ganesan; Liyang Zhang; Andrew T. Martens; Youlian Goulev; Michael B. Sherman; Johan Paulsson; Mandar T. Naik; Paul P. Sotiriadis; Eleftherios Mylonakis

Journal: Nature Communications

PubMed ID: 41803147

Doi: 10.1038/s41467-026-70348-9

Products & Services: Peptide Synthesis

Crystal structure of Alzheimer's disease phospholipase D3 provides a molecular basis for understanding its normal and pathological functions

Authors: Kenta Ishii; Stefan J. Hermans; Maria Eleni Georgopoulou; Tracy L. Nero; Nancy C. Hancock; Gabriela A. N. Crespi; Michael A. Gorman; Jonathan H. Gooi; Michael W. Parker

Journal: The FEBS journal

PubMed ID: 39325669

Doi: 10.1111/febs.17277