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How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimer's disease brain by a strain-relief mechanism

Authors: David Eisenberg, Ke Hou, Peng Ge, Michael Sawaya, Joshua Dolinsky, Yuan Yang, Yi Xiao Jiang, Liisa Lutter, David Boyer, Xinyi Cheng, Justin Pi, Jeffrey Zhang, Jiahui Lu, Shixin Yang, Zhiheng Yu, Juli Feigon

Journal: Res Sq

PubMed ID: 38766197

Doi: 10.21203/rs.3.rs-4152095/v1

Products & Services: Catalog Peptides

Optimization of quenched fluorescent peptide substrates of SARS-CoV-2 3CL main protease (Mpro) from proteomic identification of P6-P6' active site specificity

Authors: Hugo Cesar Ramos de Jesus, Nestor Solis, Yoan Machado, Isabel Pablos, Peter A Bell, Reinhild Kappelhoff, Peter M Grin, Carlos A Sorgi, Georgina S Butler, Christopher M Overall

Journal: J Virol

PubMed ID: 38742901

Doi: 10.1128/jvi.00049-24

Products & Services: Peptide Synthesis

A vector system for single and tandem expression of cloned genes and multi-colour fluorescent tagging in

Authors: Solenne Ithurbide, Roshali T de Silva, Hannah J Brown, Vinaya Shinde, Iain G Duggin

Journal: Microbiology (Reading)

PubMed ID: 38787390

Doi: 10.1099/mic.0.001461

Products & Services: Protein and Antibody Isolation

Development of a Plant-Expressed Subunit Vaccine against Brucellosis

Authors: Daria A Rutkowska, Lissinda H Du Plessis, Essa Suleman, Martha M O'Kennedy, Deepak B Thimiri Govinda Raj, Yolandy Lemmer

Journal: Microorganisms

PubMed ID: 38930429

Doi: 10.3390/microorganisms12061047

Products & Services: Catalog Peptides

Indels allow antiviral proteins to evolve functional novelty inaccessible by missense mutations

Authors: Jeannette L Tenthorey, Serena Del Banco, Ishrak Ramzan, Hayley Klingenberg, Chang Liu, Michael Emerman, Harmit S Malik

Journal: biorxiv

PubMed ID: 38765965

Doi: 10.1101/2024.05.07.592993

Products & Services: PCR Cloning and Subcloning

Transcriptome Analysis Reveals the Induction of Apoptosis-Related Genes by a Monoclonal Antibody against a New Epitope of CD99 on T-Acute Lymphoblastic Leukemia

Authors: Nuchjira Takheaw, Kamonporn Kotemul, Ratthakorn Chaiwut, Supansa Pata, Witida Laopajon, Kuntalee Rangnoi, Montarop Yamabhai, Watchara Kasinrerk

Journal: Antibodies (Basel)

PubMed ID: 38804310

Doi: 10.3390/antib13020042

Products & Services: Catalog Peptides

Production of VP3-only virus-like particles of Adeno-associated virus 2 in E coli cells

Authors: Chengyu Fu, Shruthi Gobbooru, Ashley T Martino, Woon-Kai Low

Journal: Protein Expr Purif

PubMed ID: 38754753

Doi: 10.1016/j.pep.2024.106502

Products & Services: Catalog Antibodies

Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis

Authors: Zhixin Ma, Yu Sun, Yang Yu, Wenjun Xiao, Zhijie Xiao, Tianyu Zhong, Xi Xiang, Zhigang Li

Journal: Cell Commun Signal

PubMed ID: 38802814

Doi: 10.1186/s12964-024-01669-9

Overexpression of PEX14 results in mistargeting to mitochondria, accompanied by organelle fragmentation and clustering in human embryonic kidney cells

Authors: Renate L M Jansen, Rinse de Boer, Eline M F de Lange, Janet Koster, Rifka Vlijm, Hans R Waterham, Ida J van der Klei

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 38762172

Doi: 10.1016/j.bbamcr.2024.119754

Products & Services: Molecular Biology Reagents

Deep mutational scanning reveals a correlation between degradation and toxicity of thousands of aspartoacylase variants

Authors: Martin Grønbæk-Thygesen, Vasileios Voutsinos, Kristoffer E. Johansson, Thea K. Schulze, Matteo Cagiada, Line Pedersen, Lene Clausen, Snehal Nariya, Rachel L. Powell, Amelie Stein, Douglas M. Fowler, Kresten Lindorff-Larsen & Rasmus Hartmann-Petersen

Journal: Nat Commun

PubMed ID: 38740822

Doi: 10.1038/s41467-024-48481-0

Products & Services: Mutagenesis Services