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Transcription elongation of the plant RNA polymerase IV is prone to backtracking

Authors: Chengli Fang, Kun Huang, Xiaoxian Wu, Hongwei Zhang, Zhanxi Gu, Jiawei Wang, Yu Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 39178250

Doi: 10.1126/sciadv.adq3087

Products & Services: Protein and Antibody Isolation

A two-pronged nanostrategy of iron metabolism disruption to synergize tumor therapy by triggering the paraptosis-apoptosis hybrid pathway

Authors: Huali Lei , Guanghui Hou , Lin Liu , Zifan Pei , Youdong Chen , Yujie Lu , Nalin Yang , Shumin Sun , Liang Cheng

Journal: ACS Nano

PubMed ID: 39121010

Doi: 10.1021/acsnano.4c06199

Products & Services: Peptide Synthesis

25-Hydroxycholesterol inhibits Hantavirus infection by reprogramming cholesterol metabolism

Authors: Yamei Dang , Yuan Wang , Jing Wei , Hui Zhang , Qiqi Yang , Bin Wang , Jia Li , Chuantao Ye , Yang Chen , Peijun Han , Xiaolei Jin , Jia Wang , Xiaohui Bao , He Liu , Hongwei Ma , Liang Zhang , Linfeng Cheng , Yangchao Dong , Yinlan Bai , Yinghui Li , Yingfeng Lei , Zhikai Xu , Fanglin Zhang , Wei Ye

Journal: FREE RADICAL BIOLOGY AND MEDICINE

PubMed ID: 39209137

Doi: 10.1016/j.freeradbiomed.2024.08.029

Products & Services: Codon Optimization

Activation of ATF3 via the integrated stress response pathway regulates innate immune response to restrict Zika virus

Authors: Pheonah Badu , Gabriele Baniulyte , Morgan A Sammons , Cara T Pager

Journal: Virology Journal

PubMed ID: 39212382

Doi: 10.1128/jvi.01055-24

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Reduced Cross-Protective Potential of Omicron Compared to Ancestral SARS-CoV-2 Spike Vaccines Against Potentially Zoonotic Coronaviruses

Authors: Tyler RennerMatthew StuibleBrian CassSylvie PerretJulie GuimondSimon Lord-DufourMichael J. McCluskieYves DurocherBassel Akache

Journal: npj Viruses

Doi: doi.org/10.21203/rs.3.rs-4791122/v1

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Novel peptide inhibitor for the Chikungunya virus nsP2 protease: Identification and characterization

Authors: Mohammadamin Mastalipour; Ian Gering; M nika Aparecida Coronado; Jorge Enrique Hern ndez Gonz lez; Dieter Willbold; Raphael Josef Eberle

Journal: Current Research in Microbial Sciences

PubMed ID: 40165933

Doi: 10.1016/j.crmicr.2025.100376

Products & Services: Peptide Synthesis

Integrative analysis of the therapeutic mechanisms of Astragaloside IV in idiopathic pulmonary fibrosis via network pharmacology and molecular validation

Authors: Shanshan Chen; Jin Yan; Jing Zhang; Yiwen Ma; Yiliang Su; Yiming Yu

Journal: Scientific REPORTS

PubMed ID: 41224967

Doi: 10.1038/s41598-025-23354-8

Products & Services: Protein Electrophoresis and Western

High Throughput Screening for SARS-CoV-2 Helicase Inhibitors

Authors: Yuka Otsuka; Eunjung Kim; Austin Krueger; Justin Shumate; Chao Wang; Bilel Bdiri; Sultan Ullah; HaJeung Park; Louis Scampavia; Thomas D. Bannister; Donghoon Chung; Timothy P. Spicer

Journal: SLAS discovery : advancing life sciences R & D

PubMed ID: 39173831

Doi: 10.1016/j.slasd.2024.100180

A metal anion strategy to induce pyroptosis combined with STING activation to synergistically amplify anti-tumor immunity

Authors: Zifan Pei , Nan Jiang , Fei Gong , Weihao Yang , Jiachen Xu , Bin Yu , Nailin Yang , Jie Wu , Huali Lei , Shumin Sun , Longxiao Li , Zhicheng Liu , Caifang Ni , Liang Cheng

Journal: Materials Today

Doi: 10.1016/j.mattod.2024.07.013

Products & Services: Protein and Antibody Isolation

Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression

Authors: Cheng Zhang , Hong-Ming Ma , Shuai Wu , Jia-Ming Shen , Na Zhang , Yi-Lu Xu , Cheng-Xiao Li , Ping He , Meng-Kai Ge , Xi-Li Chu , Yu-Xue Zhang , Jun-Ke Zheng , Guo-Qiang Chen , Shao-Ming Shen

Journal: Developmental Cell

PubMed ID: 39197453

Doi: 10.1016/j.devcel.2024.08.003

Products & Services: Protein Electrophoresis and Western