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Tumor nutrient stress gives rise to a drug tolerant cell state in pancreatic cancer

Authors: Colin Sheehan; Lyndon Hu; Guillaume Cognet; Grace Croley; Thao Trang Nguyen; Anika Thomas-Toth; Darby Agovino; Patrick B. Jonker; Mumina Sadullozoda; Leah M. Ziolkowski; James K. Martin; Alica K. Beutel; Ranya Dano; Mohammed A. Khan; Christopher J. Halbrook; Kay F. Macleod; Christopher R. Weber; James L. LaBelle; Alexander Muir

Journal: biorxiv

PubMed ID: 40964288

Doi: 10.1101/2025.09.04.673818

Products & Services: Peptide Synthesis

Integrative analysis of the therapeutic mechanisms of Astragaloside IV in idiopathic pulmonary fibrosis via network pharmacology and molecular validation

Authors: Shanshan Chen; Jin Yan; Jing Zhang; Yiwen Ma; Yiliang Su; Yiming Yu

Journal: Scientific REPORTS

PubMed ID: 41224967

Doi: 10.1038/s41598-025-23354-8

Products & Services: Protein Electrophoresis and Western

High Throughput Screening for SARS-CoV-2 Helicase Inhibitors

Authors: Yuka Otsuka; Eunjung Kim; Austin Krueger; Justin Shumate; Chao Wang; Bilel Bdiri; Sultan Ullah; HaJeung Park; Louis Scampavia; Thomas D. Bannister; Donghoon Chung; Timothy P. Spicer

Journal: SLAS discovery : advancing life sciences R & D

PubMed ID: 39173831

Doi: 10.1016/j.slasd.2024.100180

Highly sensitive and selective electrochemical biosensor using odorant-binding protein to detect aldehydes

Authors: Cong Peng a b, Yutong Sui a, Chaohua Fang a, Hongxu Sun a, Wenxin Liu a, Xinying Li a, Chen Qu a, Wenhui Li a, Jiemin Liu a c, Chuandong Wu a

Journal: Analytica Chimica Acta

Doi: 10.1016/j.aca.2024.342932

Products & Services: PCR Cloning and Subcloning

CLASP-mediated competitive binding in protein condensates directs microtubule growth

Authors: Xuanyan Jia , Leishu Lin, Siqi Guo , Lulu Zhou , Gaowei Jin , Jiayuan Dong , Jinman Xiao , Xingqiao Xie , Yiming Li , Sicong He , Zhiyi Wei , Cong Yu

Journal: Nature Communications

PubMed ID: 39095354

Doi: 10.1038/s41467-024-50863-3

Products & Services: Protein and Antibody Isolation

Simultaneous In Vivo Imaging of Neutrophil Elastase and Oxidative Stress in Atherosclerotic Plaques Using a Unimolecular Photoacoustic Probe

Authors: Yuan Ma , Hui Cao , Baode Chen , Xinyu Xu , Qingpeng Zhang , Haoming Chen , Xiao-Bing Zhang , Guosheng Song

Journal: ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PubMed ID: 39115358

Doi: 10.1002/anie.202411840

Products & Services: Peptide Synthesis

A broadly protective antibody targeting glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection

Authors: Xuanxiu Ren # 1, Jiawen Sun # 2 3, Wenhua Kuang # 2, Feiyang Yu 1, Bingjie Wang 1, Yong Wang 2 3, Wei Deng 2 3, Zhao Xu 2 3, Shangyu Yang 1, Hualin Wang 2 4, Yangbo Hu 2 4, Zengqin Deng 5 6, Yun-Jia Ning 7 8, Haiyan Zhao

Journal: Nature Communications

PubMed ID: 39147753

Doi: 10.1038/s41467-024-51108-z

Products & Services: Protein and Antibody Isolation

Lipid synthesis, triggered by PPARγ T166 dephosphorylation, sustains reparative function of macrophages during tissue repair

Authors: Shiman Zuo , Yuxin Wang , Hanjing Bao , Zehui Zhang , Nanfei Yang , Meng Jia , Qing Zhang , Ani Jian , Rong Ji , Lidan Zhang , Yan Lu , Yahong Huang , Pingping Shen

Journal: Nature Communications

PubMed ID: 39179603

Doi: doi.org/10.1038/s41467-024-51736-5

Products & Services: Gene Synthesis

Novel peptide inhibitor for the Chikungunya virus nsP2 protease: Identification and characterization

Authors: Mohammadamin Mastalipour; Ian Gering; M nika Aparecida Coronado; Jorge Enrique Hern ndez Gonz lez; Dieter Willbold; Raphael Josef Eberle

Journal: Current Research in Microbial Sciences

PubMed ID: 40165933

Doi: 10.1016/j.crmicr.2025.100376

Products & Services: Peptide Synthesis

Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin

Authors: Sabine Pellett; Michael P. Schwartz; William H. Tepp; Richard Josephson; Jacob M. Scherf; Christina L. Pier; James A. Thomson; William L. Murphy; Eric A. Johnson

Journal: Scientific REPORTS

PubMed ID: 26411797

Doi: 10.1038/srep14566

Products & Services: Peptide Synthesis