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The impact of HBx protein on mitochondrial dynamics and associated signaling pathways strongly depends on the hepatitis B virus genotype

Authors: Anja Schollmeier, Michael Basic, Mirco Glitscher, Eberhard Hildt

Journal: J Virol

PubMed ID: 38629837

Doi: 10.1128/jvi.00424-24

Products & Services: Molecular Biology Reagents

Sequential release of interacting proteins and Ub-modifying enzymes by disulfide heterotypic ubiquitin reagents

Authors: Hongyi Cai, Xiangwei Wu, Junxiong Mao, Zebin Tong, Dingfei Yan, Yicheng Weng, Qingyun Zheng

Journal: Bioorganic Chemistry

PubMed ID: 38387394

Doi: 10.1016/j.bioorg.2024.107186

Products & Services: Protein and Antibody Isolation

A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers

Authors: Dan-Dan Zhou, Xiao-Tian Zhai, Lan-Wen Zhang, Zi-Hui Xie, Ying Wang, Yong-Su Zhen, Rui-Juan Gao, Qing-Fang Miao

Journal: NPJ Precis Oncol

PubMed ID: 38654141

Doi: 10.1038/s41698-024-00584-z

Products & Services: Protein and Antibody Isolation

Combination of a TGF-β ligand trap (RAP-GRL) and TMPRSS6-ASO is superior for correcting β-thalassemia

Authors: Amaliris Guerra, Nolan Hamilton, Ariel Rivera, Perry Demsko, Shuling Guo, Stefano Rivella

Journal: Am J Hematol

PubMed ID: 38659383

Doi: 10.1002/ajh.27332

Products & Services: Protein and Antibody Isolation

Hymenopteran-specific TRPA channel from the Texas leaf cutter ant (Atta texana) is heat and cold activated and expression correlates with environmental temperature

Authors: Julia M York, Timothy N Taylor, Sarah LaPotin, Ying Lu, Ulrich Mueller

Journal: Insect Sci

PubMed ID: 38605428

Doi: 10.1111/1744-7917.13364

Products & Services: Molecular Biology Reagents

Cellugyrin (synaptogyrin-2) dependent pathways are used by bacterial cytolethal distending toxin and SARS-CoV-2 virus to gain cell entry

Authors: Kathleen Boesze-Battaglia, Gary H Cohen, Paul F Bates, Lisa M Walker, Ali Zekavat, Bruce J Shenker

Journal: Front Cell Infect Microbiol

PubMed ID: 38698905

Doi: 10.3389/fcimb.2024.1334224

Products & Services: Protein and Antibody Isolation

Interplay of the Tfb1 pleckstrin homology domain with Rad2 and Rad4 in transcription coupled and global genomic nucleotide excision repair

Authors: Wenzhi Gong, Hannah Holmberg, Cheng Lu, Michelle Huang, Shisheng Li

Journal: Nucleic Acids Res

PubMed ID: 38634797

Doi: 10.1093/nar/gkae286

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A DNA circuit that records molecular events

Authors: Mingzhi Zhang, Colin Yancey, Chao Zhang, Junyan Wang, Qian Ma, Linlin Yang, Rebecca Schulman, Da Han, Weihong Tan

Journal: SCIENCE ADVANCES

PubMed ID: 38578999

Doi: 10.1126/sciadv.adn3329

Products & Services: Custom DNA/RNA Oligos

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Authors: Guy J Pearson, Harriet V Mears, Malgorzata Broncel, Ambrosius P Snijders, David L V Bauer, Jeremy G Carlton

Journal: SCIENCE ADVANCES

PubMed ID: 38569033

Doi: 10.1126/sciadv.adl5012

Products & Services: Custom DNA/RNA Oligos

Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening

Authors: Xing Li, Shiyu Sun, Wansong Zhang, Ziwei Liang, Yitong Fang, Tianhu Sun, Yong Wan, Xingcong Ma, Shuqun Zhang, Yang Xu, Ruilin Tian

Journal: Experimental & Clinical Cancer Research

PubMed ID: 38561797

Doi: 10.1186/s13046-024-03027-6

Products & Services: Recombinant Proteins