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Gene replacement therapy in Bietti crystalline corneoretinal dystrophy: an open-label, single-arm, exploratory trial
Authors: Jinyuan Wang, Jinlu Zhang, Shicheng Yu, Hongyan Li, Shaohong Chen, Jingting Luo, Haibo Wang, Yuxia Guan, Haihan Zhang, Shiyi Yin, Huili Wang, Heping Li, Junle Liu, Jingyuan Zhu, Qiong Yang, Ying Sha, Chuan Zhang, Yuhang Yang, Xuan Yang, Xifang Zhang, Xiuli Zhao, Likun Wang, Liping Yang, Wenbin Wei
Journal: Signal Transduct Target Ther
PubMed ID: 38653979
Doi: 10.1038/s41392-024-01806-3
Products & Services: Catalog Peptides   
Identification of a homoarginine biosynthetic gene from a microcystin biosynthetic pathway in Fischerella sp PCC 9339
Authors: Xiaodan Ouyang, Matti Wahlsten, Maija Pollari, Endrews Delbaje, Jouni Jokela, David P Fewer
Journal: Toxicon
PubMed ID: 38670499
Doi: 10.1016/j.toxicon.2024.107733
Products & Services: Molecular Biology Reagents   
Depolymerization of SUMO chains induces slender to stumpy differentiation in T brucei bloodstream parasites
Authors: Paula Ana Iribarren, Lucía Ayelén Di Marzio, María Agustina Berazategui, Andreu Saura, Lorena Coria, Juliana Cassataro, Federico Rojas, Miguel Navarro, Vanina Eder Alvarez
Journal: PLoS Pathog
PubMed ID: 38635823
Doi: 10.1371/journal.ppat.1012166
Products & Services: Custom Vector Construction   
Stepwise activation of a metabotropic glutamate receptor
Authors: Kaavya Krishna Kumar, Haoqing Wang, Chris Habrian, Naomi R Latorraca, Jun Xu, Evan S O'Brien, Chensong Zhang, Elizabeth Montabana, Antoine Koehl, Susan Marqusee, Ehud Y Isacoff, Brian K Kobilka
Journal: Nature
PubMed ID: 38632403
Doi: 10.1038/s41586-024-07327-x
Products & Services: Catalog Antibodies   
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
Authors: Jack D Chan, Christina M Scheffler, Isabelle Munoz, Kevin Sek, Joel N Lee, Yu-Kuan Huang, Kah Min Yap, Nicole Y L Saw, Jasmine Li, Amanda X Y Chen, Cheok Weng Chan, Emily B Derrick, Kirsten L Todd, Junming Tong, Phoebe A Dunbar, Jiawen Li, Thang X Hoang, Maria N de Menezes, Emma V Petley, Joelle S Kim, Dat Nguyen, Patrick S K Leung, Joan So, Christian Deguit, Joe Zhu, Imran G House, Lev M Kats, Andrew M Scott, Benjamin J Solomon, Simon J Harrison, Jane Oliaro, Ian A Parish, Kylie M Quinn, Paul J Neeson, Clare Y Slaney, Junyun Lai, Paul A Beavis, Phillip K Darcy
Journal: Nature
PubMed ID: 38600376
Doi: 10.1038/s41586-024-07242-1
Products & Services: Molecular Biology Reagents   
Transmembrane conformation of the envelope protein of an alpha coronavirus, NL63
Authors: Iva Sučec, Yanina Pankratova, Mriganka Parasar, Mei Hong
Journal: Protein Sci
PubMed ID: 38501465
Doi: 10.1002/pro.4923
Products & Services: Custom Vector Construction   
Tumor vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA): Suppresses macrophage capping protein beyond STING activation
Authors: Zhiyong Xiao, Xia Cui, Feng Liu, Ying Wang, Xiao Liu, Wenxia Zhou, Yongxiang Zhang
Journal: Biochim Biophys Acta Mol Basis Dis
PubMed ID: 38565383
Doi: 10.1016/j.bbadis.2024.167149
Products & Services: Protein and Antibody Isolation   
Structural analyses of the GI4 norovirus by cryo-electron microscopy and X-ray crystallography revealing binding sites for human monoclonal antibodies
Authors: Tomomi Kimura-Someya, Kazushige Katsura, Miyuki Kato-Murayama, Toshiaki Hosaka, Tomomi Uchikubo-Kamo, Kentaro Ihara, Kazuharu Hanada, Shin Sato, Kazutaka Murayama, Michiyo Kataoka, Mikako Shirouzu, Yuichi Someya
Journal: J Virol
PubMed ID: 38593321
Doi: 10.1128/jvi.00197-24
Products & Services: Gene Synthesis   
mARC1 in MASLD: Modulation of lipid accumulation in human hepatocytes and adipocytes
Authors: Amanda K Jones, Besnik Bajrami, Morgan K Campbell, Abdullah Mesut Erzurumluoglu, Qiusha Guo, Hongxing Chen, Xiaomei Zhang, Svetlana Zeveleva, David Kvaskoff, Andreas-David Brunner, Stefanie Muller, Vasudha Gathey, Rajvee M Dave, James W Tanner, Sophia Rixen, Michel A Struwe, Kathryn Phoenix, Kaitlyn J Klumph, Heather Robinson, Daniel Veyel, Annkatrin Muller, Boris Noyvert, Boris Alexander Bartholdy, Agnes A Steixner-Kumar, Jan Stutzki, Dmitriy Drichel, Steffen Omland, Ryan Sheehan, Jon Hill, Tom Bretschneider, Dirk Gottschling, Axel J Scheidig, Bernd Clement, Martin Giera, Zhihao Ding, John Broadwater, Curtis R Warren
Journal: Hepatol Commun
PubMed ID: 38619429
Doi: 10.1097/HC9.0000000000000365
Products & Services: Molecular Biology Reagents   
Probing actin-activated ATP turnover kinetics of human cardiac myosin II by single molecule fluorescence
Authors: Albin Berg, Lok Priya Velayuthan, Sven Tågerud, Marko Ušaj, Alf Månsson
Journal: Cytoskeleton (Hoboken)
PubMed ID: 38623952
Doi: 10.1002/cm.21858
Products & Services: Molecular Biology Reagents   
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