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Streptococcus pneumoniae endopeptidase O induces trained immunity and confers protection against various pathogenic infections

Authors: Wenlong Xu, Yuan Yuan, Zhaoche Shu, Ting Guo, Bichen Liu, Jiangming Xiao, Lian Li, Yibin Yin, Xuemei Zhang

Journal: Clin Immunol

PubMed ID: 38663493

Doi: 10.1016/j.clim.2024.110226

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An Omicron-specific, self-amplifying mRNA booster vaccine for COVID-19: a phase 2/3 randomized trial

Authors: Amit Saraf, Rohan Gurjar, Swarnendu Kaviraj, Aishwarya Kulkarni, Durgesh Kumar, Ruta Kulkarni, Rashmi Virkar, Jayashri Krishnan, Anjali Yadav, Ekta Baranwal, Ajay Singh, Arjun Raghuwanshi, Praveen Agarwal, Laxman Savergave, Sanjay Singh; GEMCOVAC-OM Study Investigators

Journal: nature medicine

PubMed ID: 38637636

Doi: 10.1038/s41591-024-02955-2

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AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans

Authors: Lilit Grigoryan, Yupeng Feng, Lorenza Bellusci, Lilin Lai, Bushra Wali, Madison Ellis, Meng Yuan, Prabhu S Arunachalam, Mengyun Hu, Sangeeta Kowli, Sheena Gupta, Sofia Maysel-Auslender, Holden T Maecker, Hady Samaha, Nadine Rouphael, Ian A Wilson, Alberto C Moreno, Mehul S Suthar, Surender Khurana, Stéphane Pillet, Nathalie Charland, Brian J Ward, Bali Pulendran

Journal: Science immunology

PubMed ID: 38579013

Doi: 10.1126/sciimmunol.adi8039

Products & Services: Gene Synthesis

Dbf4-dependent kinase promotes cell cycle controlled resection of DNA double-strand breaks and repair by homologous recombination

Authors: Lorenzo Galanti, Martina Peritore, Robert Gnügge, Elda Cannavo, Johannes Heipke, Maria Dilia Palumbieri, Barbara Steigenberger, Lorraine S Symington, Petr Cejka, Boris Pfander

Journal: Nature Communications

PubMed ID: 38570537

Doi: 10.1038/s41467-024-46951-z

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CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits

Authors: Annemart Koornneef, Kanika Vanshylla, Gijs Hardenberg, Lucy Rutten, Nika M Strokappe, Jeroen Tolboom, Jessica Vreugdenhil, Karin Feddes-de Boer, Aditya Perkasa, Sven Blokland, Judith A Burger, Wei-Chiao Huang, Jonathan F Lovell, Danielle van Manen, Rogier W Sanders, Roland C Zahn, Hanneke Schuitemaker, Johannes P M Langedijk, Frank Wegmann

Journal: Nature Communications

PubMed ID: 38605096

Doi: 10.1038/s41467-024-47492-1

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Dual-responsive nanocarriers for efficient cytosolic protein delivery and CRISPR-Cas9 gene therapy of inflammatory skin disorders

Authors: Echuan Tan, Tao Wan, Qi Pan, Jianan Duan, Song Zhang, Ruijue Wang, Peng Gao, Jia Lv, Hui Wang, Dali Li, Yuan Ping, Yiyun Cheng

Journal: SCIENCE ADVANCES

PubMed ID: 38630829

Doi: 10.1126/sciadv.adl4336

Engineering allorejection-resistant CAR-NKT cells from hematopoietic stem cells for off-the-shelf cancer immunotherapy

Authors: Yan-Ruide Li, Yang Zhou 1, Jiaji Yu, Yichen Zhu, Derek Lee, Enbo Zhu, Zhe Li, Yu Jeong Kim, Kuangyi Zhou, Ying Fang, Zibai Lyu, Yuning Chen, Yanxin Tian, Jie Huang, Xinjian Cen, Tiffany Husman, Jae Min Cho, Tzung Hsiai, Jin J Zhou, Pin Wang, Benjamin R Puliafito, Sarah M Larson, Lili Yang

Journal: Molecular Therapy

PubMed ID: 38584391

Doi: 10.1016/j.ymthe.2024.04.005

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The hsa_circ_0082152 maintains NF-κB mRNA stability by binding to MTDH to promote anti-tuberculosis drug-induced liver injury

Authors: Lin Wang, Chunyan Meng, Yifei Long, Yue Liu, Luming Yang, Xuelei Gao, Shufeng Sun, Fumin Feng

Journal: Int J Biol Macromol

PubMed ID: 38670193

Doi: 10.1016/j.ijbiomac.2024.131793

Products & Services: Molecular Biology Reagents

LncRNA BlncAD1 Modulates Bovine Adipogenesis by Binding to MYH10, PI3K/Akt Signaling Pathway, and miR-27a-5p/CDK6 Axis

Authors: Xin Li, Zhongyi Hou, Shengbo Meng, Qihui Jia, Shanshan Xing, Zhitong Wang, Mengjuan Chen, Huifen Xu, Ming Li, Hanfang Cai

Journal: J Agric Food Chem

PubMed ID: 38661523

Doi: 10.1021/acs.jafc.4c00165

Products & Services: Molecular Biology Reagents

The Bifunctional Effects of Lactoferrin (LFcinB11) in Inhibiting Neural Cell Adhesive Molecule (NCAM) Polysialylation and the Release of Neutrophil Extracellular Traps (NETs)

Authors: Bo Lu, Si-Ming Liao, Shi-Jie Liang, Li-Xin Peng, Jian-Xiu Li, Xue-Hui Liu, Ri-Bo Huang, Guo-Ping Zhou

Journal: Int J Mol Sci

PubMed ID: 38731861

Doi: 10.3390/ijms25094641

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