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Argonaute-mediated RNA editing selectively repairs point mutations

Authors: Zhiwei Zhang, Jinyue Wang, Tongyu Guo, Xiaolan Yu, Fei Wang, Hang Zhang, Yang Liu, Wenqiang Li, Yibin Cheng, Yanhong Peng, Guangbo Yan, Jiakai Cui, Lixin Ma

Journal: Nucleic Acids Research

PubMed ID: 41495892

Doi: 10.1093/nar/gkaf1403

Products & Services: Molecular Biology Reagents

Structural evolution of the selectivity clamp confers ADPR-PP specificity in Namat, a phage nicotinamide ADP-ribose transferase

Authors: Meimei Lan, Li Xu, Yizhen Han, Tong Cui, Zhi Qiao, Yan-Bin Teng, Na Wang, Hongyu Bao

Journal: Nucleic Acids Research

PubMed ID: 41495901

Doi: 10.1093/nar/gkaf1492

Products & Services: Gene Synthesis

Structure and function of the nairovirus cap-snatching endonuclease

Authors: Wenhua Kuang, Zhenhua Tian, Gan Zhang, Fan Wu, Jinyue Li, Jingjing Tang, Huanyu Zhang, Xinyue Zhuo, Zhihong Hu, Manli Wang, Haiyan Zhao, Zengqin Deng

Journal: Nucleic Acids Research

PubMed ID: 41533578

Doi: 10.1093/nar/gkaf1515

Products & Services: Protein and Antibody Isolation

Strategic variations in sarbecovirus and merbecovirus Nsp1 linker regions for translation inhibition

Authors: Ruixi Yan, Mingbo Wu, Xiangyu Ge, Qianqian Jin, Moyu Wang, Haolong Zhou, Yan Li, Yue Wang, Shuai Yuan

Journal: Nucleic Acids Research

PubMed ID: 41538319

Doi: 10.1093/nar/gkag017

Products & Services: Protein and Antibody Isolation

From Natural Discovery to AI-Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

Authors: Qi Yao, Jin Gao, Keling Wang, Yufeng Liu, Peijin Han, Hong Pan, Xiaofeng Yang, Qianlan Yin, Dating Zhong, Lu Ye, Qi Deng, Lingling Gao, Xiaoyu Tu, Dequan Wang, Yuming Lu

Journal: Advanced Science

PubMed ID: 41486594

Doi: 10.1002/advs.202516600

Structure-Guided Engineering of a Cas12i Nuclease Unlocks Near-PAMless Genome Editing

Authors: Qitong Chen, Hanlin Gou, Chao Xu, Sihan Wang, Huitao Zhang, Minglei Song, Mengge Wang, Xingkun Ji, Xiaofei Wei, Yuanyan Tan, Hehua Quan, Pengyu Luo, Hanyu Shou, Pengpeng Liu, Yafeng Liang, Jian-Kang Zhu

Journal: Advanced Science

PubMed ID: 41532605

Doi: 10.1002/advs.202516670

Products & Services: Synthetic Guide RNA

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS-STING Activation for Cancer Immunotherapy

Authors: Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang

Journal: Advanced Science

PubMed ID: 41560305

Doi: 10.1002/advs.202518356

Products & Services: Protein Electrophoresis and Western

A High Soluble-Fibre Allele in Wheat Encodes a Defective Cell Wall Peroxidase Responsible for Dimerization of Ferulate Moieties on Arabinoxylan

Authors: Rowan A C Mitchell, Ondrej Kosik, Abdul Kader Alabdullah, Anneke Prins, Maria Oszvald, Till K Pellny, Jackie Freeman, Kirstie Halsey, Caroline A Sparks, Alison Huttly, James Brett, Michelle Leverington-Waite, Simon Griffiths, Peter R Shewry, Alison Lovegrove

Journal: Plant Biotechnology Journal

PubMed ID: 41482806

Doi: 10.1111/pbi.70527

Products & Services: Gene Synthesis

Chemical inhibition of a bacterial immune system

Authors: Zhiyu Zang; Olivia K. Duncan; Dziugas Sabonis; Iana Fedorova; Yun Shi; Gause Miraj; Shuai Le; Jun Deng; Yuhao Zhu; Yanyao Cai; Chengqian Zhang; Garima Arya; Shelley A. H. Dixon; Steven P. Angus; Breck A. Duerkop; Haihua Liang; Robert H. Pepin; Thomas Ve; Joseph Bondy-Denomy; Giedre Tamulaitiene; Joseph P. Gerdt

Journal: Cell Host & Microbe

PubMed ID: 41619738

Doi: 10.1016/j.chom.2026.01.003

Development of an ultrahigh affinity, trimeric ACE2 biologic as a universal SARS-CoV-2 antagonist

Authors: Juliet Gonzales; Tynan Young; Hyeran Choi; Miso Park; Yead Jewel; Chengcheng Fan; Rahul Purohit; Pamela J. Bjorkman; John C. Williams

Journal: Communications Biology

PubMed ID: 41053501

Doi: 10.1038/s42003-025-08819-w