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Development and characterization of a recombinant， hypoallergenic， peptide-based vaccine for grass pollen allergy.

J. Allergy Clin. Immunol.. 2015-05; 
Focke-TejklMargarete，WeberMilena，NiespodzianaKatarzyna，NeubauerAngela，HuberHans，HenningRainer，StegfellnerGottfried，MadereggerBernhard，HauerMartina，StolzFrank，NiederbergerVerena，MarthKatharina，Eckl-DornaJulia，WeissRichard，ThalhamerJosef，BlattKatharina，ValentPeter，ValentaRu
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Plasmid DNA Preparation … Codon-optimized DNAs encoding fusion proteins consisting of allergen-derived peptides fused to the N- and C-terminus of PreS and containing a C-terminal hexahistidine tag were synthesized (GenScript, Piscataway, NJ) and inserted into the NdeI/XhoI sites of plasmid pET … Get A Quote

摘要

Grass pollen is one of the most important sources of respiratory allergies worldwide.

关键词

Grass pollen allergy，allergen，allergen-specific immunotherapy，peptide-carrier technology，recombinant allergen，recombinant hypoallergenic allergen deriva
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