More than just inflammation: Ureaplasma species induce apoptosis in human brain microvascular endothelial cells.

Ureaplasma species (spp.) are commonly regarded as low-virulent commensals but may cause invasive diseases in immunocompromised adults and in neonates， including neonatal meningitis. The interactions of Ureaplasma spp. with host defense mechanisms are poorly understood. This study addressed Ureaplasma-driven cell death， concentrating on apoptosis as well as inflammatory cell death.

Apoptosis，Caspase，HBMEC，Meningitis，Neuroinflammation，Ureaplasma parvum，Ureaplasma urealyt