Figure 1. CP-55940-induced concentration-dependent stimulation of intracellular cAMP in CHO-K1/CNR2 cells. The EC₅₀ of CP-55940 on this cell was 0.11 μM. Ratio = A660nm/B620nm x 10⁴

CHO-K1/CB2 Stable Cell Line

The Cannabinoid receptor 2 (CNR2) is a Gi/o-coupled GPCR expressed in spleen, tonsils, bone marrow and peripheral blood leukocytes. There is one report that cannabinoid-induced inhibition of helper T cell activation is lost in macrophages obtained from CNR2 knockout mice. CNR2 is a potential therapeutic target in the treatment of various disease conditions, such as pain, multiple sclerosis, vascular disease, Parkinson's disease, and other central nerve system disorders.

产品编号	M00433
规格	2 vials 定制报价
数量
价格	询价


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Synonyms

CB2 receptor, Peripheral cannabinoid receptor, CB2, CB-2, cannabinoid receptor 2, cannabinoid receptor 2 gene, rCB2, CB2-R, cannabinoid receptor 2 (spleen)

产品概述

Applications

Functional assay for CB2 receptor

产品简介

Storage	Liquid nitrogen immediately upon delivery
Species	Human

培养条件

Freeze Medium	45% culture medium, 45% FBS (Cat. #10099-141, Gibco), 10% DMSO (Cat. #D2650, Sigma)
Culture Medium	Ham’s F-12K (Kaighn’s), 10% FBS, 400 µg/ml G418 (Cat. #10131-035, Gibco)

图例

Figure 1. CP-55940-induced concentration-dependent stimulation of intracellular cAMP in CHO-K1/CNR2 cells. The EC₅₀ of CP-55940 on this cell was 0.11 μM. Ratio = A660nm/B620nm x 10⁴