Figure IL-8 induced concentration-dependent stimulation of intracellular calcium mobilization in CHO-K1/CXCR1/Gα15 cells. The cells were loaded with Calcium-4 prior to being stimulated with agonist IL-8. The intracellular calcium change was normalized and measured by FLIPR. The relative fluorescent units (RFU) were normalized and plotted against the log of the cumulative doses of IL-8 (Mean ± SD, n = 2). The EC50 of IL-8 on this cell was 0.11 µg/ml.
CHO-K1/Gα15/CXCR1
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