CHO-K1/CTLA4 Stable Cell Line
M00530 | |
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询价 | |
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联系我们 |
M00530 | |
|
|
询价 | |
|
|
|
|
联系我们 |
CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and downregulates immune responses. CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an "off" switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.<br/> |
ALPS5; CD; CD152; CELIAC3; GRD4; GSE; IDDM12
Applications | Binding assay or use as immunogen. |
Storage | Liquid nitrogen immediately upon receiving |
Species | Human |
Stability | 15 passages |
Freeze Medium | 95% complete growth medium, 5% (V/V) DMSO (Cat. #D2650, Sigma) |
Culture Medium | F-12K (Kaighn’s), 10% FBS, 8 μg/ml Puromycin (Cat. #A11138-03, Gibco) |