CHO-K1/Cyno HVEM Stable Cell Line
M00648 | |
|
|
询价 | |
|
|
|
|
联系我们 |
M00648 | |
|
|
询价 | |
|
|
|
|
联系我们 |
HVEM is found on the surface of various cell types, including hematopoietic and non-hematopoietic cells, and is expressed mainly in spleen, thymus, bone marrow, lung and intestines. It has been identified as a canonical TNF receptor, signaling through the TNF receptor-associated factors (TRAFs) leading to NFκB activation. Furthermore, in addition to acting as a signaling receptor, in binding to Ig superfamily members it acts as a ligand for these inhibitory receptors. Therefore, bidirectional signaling is possible for the HVEM-mediated signaling network, which can be involved in positive or negative immunological reactions under different contexts. |
Applications | Binding assay or use as immunogen |
Storage | Liquid nitrogen immediately upon receiving |
Species | Cyno |
Stability | 15 passages |
Freeze Medium | 95% complete growth medium, 5% DMSO |
Culture Medium | F12K, 10% FBS, 8 μg/ml Puromycin |