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Atrial Natriuretic Peptide (ANP) (1-28), human, porcine

Atrial natriuretic peptide (ANP), a stimulator of particulate guanylate cyclase, has been found to protect against reoxygenation-induced hypercontracture in isolated cardiomyocytes by increasing cyclic guanosine monophosphate synthesis; ANP also contributes to stimulation of lipolysis during repeated bouts of exercise and in the control of lipolysis during exercise.
RP11927
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Synonyms ANP (1-28), human, porcineANP(1-28)
Description Atrial natriuretic peptide (ANP), a stimulator of particulate guanylate cyclase, has been found to protect against reoxygenation-induced hypercontracture in isolated cardiomyocytes by increasing cyclic guanosine monophosphate synthesis; ANP also contributes to stimulation of lipolysis during repeated bouts of exercise and in the control of lipolysis during exercise.
Sequence
{SER}{LEU}{ARG}{ARG}{SER}{SER}{CYS}{PHE}{GLY}{GLY}{ARG}{MET}
{ASP}{ARG}{ILE}{GLY}{ALA}{GLN}{SER}{GLY}{LEU}{GLY}{CYS}{ASN}
{SER}{PHE}{ARG}{TYR}
Sequence Shortening SLRRSSCFGGRMDRIGAQSGLGCNSFRY (Disulfide bridge: 7-23)
Molecular Formula C127H203N45O39S3
Disulfide Bridge Cys7-Cys23
Molecular Weight 3080.5

Purity > 95%
Solubility Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
Form Lyophilized
Storage Store at -20°C. Keep tightly closed. Store in a cool dry place.


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