eSpCas9 mRNA(Cap1, m1Ψ)

The eSpCas9 mRNA expresses enhanced-specificity SpCas9 protein, with sequence originally from Slaymaker et al Science. 2015 Dec 1. eSpCas9 is able to reduce off-target effects by over 10-fold, while maintaining robust on-target genome editing efficiency. This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.

产品编号	RP-A00018
规格	0.1 mg 0.2 mg 1 mg 大单询价
数量
价格	￥1000


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产品简介

产品介绍	The eSpCas9 mRNA expresses enhanced-specificity SpCas9 protein, with sequence originally from Slaymaker et al Science. 2015 Dec 1. eSpCas9 is able to reduce off-target effects by over 10-fold, while maintaining robust on-target genome editing efficiency. This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.
产品浓度	1mg/mL
存储溶液	1mM Sodium citrate, pH6.5
mRNA序列全长	4479nt
mRNA全长分子量	1457890
储存条件	Store at -20°C for short term (<3 months), store at -80°C for long term.