GenLNP-A01-FLuc mRNA (m1Ψ)

The GenLNP-A01-FLuc mRNA (m1Ψ) is a LNP formulation loaded with firefly luciferase mRNA (m1Ψ) prepared using generic LNP formulation with main ionizable lipid of ALC0315. The payload Fluc mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudo-Uridine. F-Luc mRNA can translate into F-Luc and emit bioluminescence in the presence of its substrate, Luciferin. Fluc mRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. This formulation is a good control for testing if ALC0315 LNP formulation is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model.