GenLNP-L01-FLuc mRNA (m1Ψ)

The LNP formulation loaded with firefly luciferase mRNA (m1Ψ) is prepared using generic LNP formulation with main ionizable lipid of LP01. The payload Fluc mRNA (m1Ψ) has all the U bases 100% modified with N1-methyl-pseudo-Uridine. F-Luc mRNA can translate into F-Luc and emit bioluminescence in the presence of its substrate, Luciferin. Fluc mRNA is a commonly used fluorescence reporter sequence in mRNA therapeutics and delivery system development projects. This formulation is a good control for testing if LP01 LNP formulation is a good potential formulation for your mRNA product under research in your in vitro and in vivo experiment model