PE2/PE3 mRNA (Cap1, m1Ψ)

Prime editing (PE) systems minimally consist of two components: a programmable DNA nickase fused to an engineered reverse transcriptase and a pegRNA. The PE2/PE3 mRNA sequence was from publication: Nelson, et al. Nat Biotechnology, 2022; 40: 402-410. This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.

产品编号	RP-A00044
规格	0.1 mg 0.2 mg 1 mg 大单询价
数量
价格	￥1000


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产品简介

产品介绍	Prime editing (PE) systems minimally consist of two components: a programmable DNA nickase fused to an engineered reverse transcriptase and a pegRNA. The PE2/PE3 mRNA sequence was from publication: Nelson, et al. Nat Biotechnology, 2022; 40: 402-410. This mRNA is capped with Cap1 structure with high capping efficiency. It has 100% substituted with N1-methyl-pseudo Uridine for enhanced expression and reduced immunogenicity. The mRNA has a 100A tail in its sequence, mimics a mature mRNA.
产品浓度	1mg/mL
存储溶液	1mM Sodium citrate, pH6.5
mRNA序列全长	6652nt
mRNA全长分子量	2167186
储存条件	Store at -20°C for short term (<3 months), store at -80°C for long term.