Her2, Avi & His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Her2, Avi & His, Human is greater than 95% as determined by SEC-HPLC.

Immobilized Her2, Avi & His, Human at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HER2 Antibody, hFc Tag with the EC50 of 7.4 ng/ml determined by ELISA.

Her2, Avi & His, Human

ErbB2, also known as Neu and Her2, is a type I membrane glycoprotein belonging to the ErbB family of tyrosine kinase receptors. It serves as a receptor for the epidermal growth factor (EGF) family of growth factors. Upon activation, ERBB2 triggers the MEMO1-RHOA-DIAPH1 signaling pathway, leading to the phosphorylation and inhibition of GSK3B at the cell membrane.

产品编号	Z03806
规格	100 μg 500 μg 大单询价
数量
价格	￥3300


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产品简介

Species

Human

Protein Construction

Her2 (Thr23-Thr652) Accession # P04626-1	His tag	Avi tag
N-term		C-term

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Immobilized Her2, Avi & His, Human (Cat.No.: Z03806) at 0.5 μg/ml can bind Anti-Her2 Antibody.

Expression System

HEK293

Theoretical Molecular Weight

72.3 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4.

Reconstitution

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage & Stability

Upon receiving, the lyophilized product remains stable up to 6 months at -20 °C or below as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

图例

Her2, Avi & His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Her2, Avi & His, Human is greater than 95% as determined by SEC-HPLC.

Immobilized Her2, Avi & His, Human at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HER2 Antibody, hFc Tag with the EC50 of 7.4 ng/ml determined by ELISA.

技术背景

Target Background	ErbB2, also known as Neu and Her2, is a type I membrane glycoprotein belonging to the ErbB family of tyrosine kinase receptors. It serves as a receptor for the epidermal growth factor (EGF) family of growth factors. Upon activation, ERBB2 triggers the MEMO1-RHOA-DIAPH1 signaling pathway, leading to the phosphorylation and inhibition of GSK3B at the cell membrane.
Synonyms	EGFR2; ErbB2; HER2; HER-2; TKR1; ERBB2;

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.