Species |
Human |
Protein Construction |
His tag |
DLL3, His, Human (Ala27-Arg490 ) Accession # Q9NYJ7-1 |
N-term |
C-term |
|
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin Level |
Less than 1 EU per μg by the LAL method. |
Biological Activity |
Immobilized DLL3, His, Human (Cat.No.: Z03813) at 0.1 μg/ml can bind Anti-DLL3 Antibody. |
Expression System |
HEK293 |
Theoretical Molecular Weight |
50.4 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 52-60 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from 0.22 μm filtered solution in PBS, 200 mM Arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Storage & Stability |
Upon receiving, the lyophilized product remains stable up to 6 months at -20 °C or below as supplied from date of receipt.
-80°C for 3 months after reconstitution.
2-8°C for 2-7 days after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Target Background |
DLL3, a transmembrane protein in the Delta/Serrate/Lag-2 (DSL) family of Notch ligands, inhibits primary neurogenesis and helps divert neurons along specific differentiation pathways. It also contributes to the formation of somite boundaries during paraxial mesoderm segmentation. |
Synonyms |
Delta3; DLL3; Pudgy; SCDO1; SCDO1delta3 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.