Immobilized GUCY2C/Guanylyl cyclase C hFc Chimera, Human at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-GUCY2C Antibody, hFc Tag with the EC50 of 15.4ng/ml determined by ELISA.

GUCY2C/Guanylyl cyclase C hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of GUCY2C/Guanylyl cyclase C hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

GUCY2C/Guanylyl cyclase C hFc Chimera, Human

Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.

产品编号	Z03912
规格	100 μg 500 μg 大单询价
数量
价格	￥3500


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产品简介

Species

Human

Protein Construction

GUCY2C/Guanylyl cyclase C (Ser24-Gln430) Accession # P25092-1	hFc
N-term	C-term

Purity

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

Endotoxin Level

Less than 1EU per μg by the LAL method.

Biological Activity

Immobilized GUCY2C/Guanylyl cyclase C hFc Chimera, Human (Cat.No.: Z03912) at 5 μg/ml (100μl/Well) on the plate can bind Biotinylated Anti-GUCY2C Antibody, hFc Tag

Expression System

HEK293

Theoretical Molecular Weight

72.8 kDa

Apparent Molecular Weight

Due to glycosylation, the protein migrates to 85-115 kDa based on Bis-Tris PAGE result.

Formulation

Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4.

Reconstitution

It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH₂O more than 100 μg/ml.

Storage & Stability

Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.

图例

GUCY2C/Guanylyl cyclase C hFc Chimera, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of GUCY2C/Guanylyl cyclase C hFc Chimera, Human is greater than 95% as determined by SEC-HPLC.

技术背景

Target Background	Guanylyl cyclase C (GUCY2C) has canonical centrality in defense of key intestinal homeostatic mechanisms, encompassing fluid and electrolyte balance, epithelial dynamics, antitumorigenesis, and intestinal barrier function. GUCY2C may represent a new target for anti-obesity pharmacotherapy.
Synonyms	Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.